TIME Framework — Wound Bed Preparation

T
Tissue
Non-viable or deficient tissue requiring debridement
I
Infection / Inflammation
Bacterial burden or prolonged inflammation impeding healing
M
Moisture
Imbalance — too dry (necrosis) or too wet (maceration)
E
Edge
Non-advancing or undermined wound edges
TTissue Types
TypeColourCharacteristics
NecroticBlack/BrownHard eschar or soft moist necrosis; devitalised; must assess stability
SloughYellow/TanDevitalised soft fibrinous tissue; stringy or mucinous; impedes healing
GranulationRed/PinkHealthy vascular tissue; granular, moist; bleeds easily; target tissue
EpithelialisationPink/WhiteNew epithelium migrating from edges; fragile; do not disturb
HypergranulationBright red raisedOvergranulation above wound margins; treat with foam pressure or silver
MWound Measurement

Linear Measurement (cm)

  • Length — head to toe orientation (longest dimension)
  • Width — side to side (perpendicular to length)
  • Depth — deepest point using sterile cotton-tipped applicator
  • Record as L × W × D cm at each assessment

Undermining & Tunnelling

  • Use clock-face method: 12 o'clock = head; 6 o'clock = feet
  • Measure deepest extent with probe; document direction and depth in cm
  • Tunnelling: narrow sinus tract extending from wound base

Photography Standardisation

  • Same camera, distance (30–40 cm), angle (90°), and lighting
  • Include ruler/scale reference in frame
  • Obtain written consent; store securely (HIPAA/local equivalent)
  • Label with patient ID, date, wound site, stage
Obtain patient consent for wound photography — particularly important in GCC cultural context.

Exudate Assessment

AAmount
  • None — wound bed dry
  • Low — wound bed moist, no saturation
  • Moderate — dressing saturated ≤50%
  • Heavy — dressing fully saturated, leaking
TType
  • Serous — clear/pale, normal acute healing
  • Haemoserous — pink-red, blood-tinged; normal or mild trauma
  • Sanguineous — bright red blood; vessel damage
  • Purulent — yellow/green/thick; infection indicator
SSmell
  • Malodour strongly associated with infection (Pseudomonas — sweet; anaerobes — fetid)
  • Document: none / mild / moderate / severe
  • Assess before cleansing; certain dressings (honey/alginate) alter odour normally

Periwound Skin Assessment

Maceration

White/grey soggy skin from excessive moisture; reduce exudate with absorbent dressing; apply barrier film/cream 3–5 cm from wound edge.

Excoriation

Superficial skin loss from enzymatic activity of exudate or friction; protect with zinc oxide paste or silicone barrier film; change dressing more frequently.

Erythema

Redness: differentiate blanching (pressure/irritation) from non-blanching (deep tissue injury or infection spreading cellulitis requiring urgent review).

Induration

Firm, hardened tissue; sign of deep infection or oedema; measure extent (cm from wound edge) and monitor closely.

Callus

Hyperkeratotic skin common around diabetic foot wounds and venous ulcers; regular debridement required to allow accurate edge assessment.

Hyperpigmentation

Haemosiderin staining common in venous disease on darker skin tones (common in GCC population); differentiate from early cellulitis clinically.

PUSH Tool — Pressure Ulcer Scale for Healing

PPUSH Tool 3.0 (NPIAP) — Total Score Range: 0–17

Monitor healing over time. Decreasing score = healing progression. Score of 0 = healed wound.

Parameter012345
Length × Width (cm²)0<0.30.3–0.60.7–1.01.1–2.02.1–3.0
6: 3.1–4.07: 4.1–8.08: 8.1–12.09: 12.1–24.010: >24.0
Exudate AmountNoneLightModerateHeavy
Tissue TypeClosedEpithelialGranulationSloughNecrotic
Complete PUSH Tool at each dressing change. Plot on graph to visualise healing trajectory. Required documentation in many GCC hospitals (CBAHI/JCI standards).
Moist Wound Healing Principle (Winter, 1962): Wounds heal 50% faster under moist conditions vs dry. Moist environment supports cell migration, autolytic debridement, and reduces pain. Avoid dry, adherent dressings on healing wounds.

Dressing Categories — Selection Guide

Dressing TypePrimary IndicationsExudate LevelChange FrequencyKey Precautions
Hydrocolloid
DuoDERM, Comfeel
Low–moderate exudate; autolytic debridement; partial thickness; protecting intact skin Low–Moderate 3–7 days (change when edge lifting >2 cm) Avoid on infected wounds; yellow gel on removal is NORMAL (not pus)
Hydrogel
Intrasite, NovaBay
Dry/necrotic wounds rehydration; burns; painful wounds (cooling effect) None–Low Daily to every 3 days Cover with secondary dressing; avoid on heavy exudate (maceration risk)
Alginate
Kaltostat, Sorbsan
High exudate; haemostasis; cavity packing; fungating wounds Moderate–Heavy Daily to every 3 days depending on exudate Do NOT use on dry wounds (can desiccate); irrigate to remove; need secondary dressing
Foam Dressing
Mepilex, Allevyn
Moderate–heavy exudate; cavity wounds (cavity foam); post-op wounds; pressure injury prevention Moderate–Heavy 2–7 days (exudate dependent) Silicone foam for fragile/periwound skin; ensure good adhesion to prevent shear
Silver Dressing
Mepilex Ag, Aquacel Ag
Critically colonised or infected wounds; biofilm management; 2-week treatment trial maximum Low–Heavy 2–7 days (product specific) Limit to 2-week trial; reassess; avoid in patients with silver sensitivity; do not use indefinitely
Manuka Honey
Medihoney, Activon
Infected/malodorous wounds; debriding; biofilm; Manuka ≥18+ UMF required Low–Moderate Daily to every 3 days Warn patient of initial stinging (osmotic effect); may increase exudate; check halal status per formulary
NPWT / VAC
KCI VAC, Renasys
Complex cavity wounds; dehisced surgical; grafts; high exudate; stimulate granulation Heavy Every 48–72 hours (continuous or intermittent mode) Contraindicated: untreated osteomyelitis, malignancy in wound, unexplored fistula, exposed vessels/nerves
Hydrofibre
Aquacel, Durafiber
High exudate; fragile periwound skin; deep cavity; infected wounds (Ag version) Moderate–Heavy Daily to every 3 days Gel-forming on contact; need secondary dressing; superior to alginate for fragile periwound
Iodine
Iodosorb (cadexomer), Betadine
Infected wounds; chronic infected sloughy wounds; cadexomer preferred for chronic wounds Low–Moderate Every 2–3 days (cadexomer); change when pale Avoid in thyroid disorders, large wounds (systemic iodine absorption), pregnancy; limit use to short course
Biological
MEBO, Collagen, Larval
Non-healing chronic wounds; larval therapy for necrotic/sloughy wounds Variable Larval: every 48–72 hrs; collagen: per protocol Larval therapy requires specialist prescribing; patient acceptance counselling; check GCC availability
!Silver Dressing — 2-Week Rule

Silver dressings should be used as a 2-week treatment trial only, then reassessed:

  • If wound improving → step down to standard moist dressing
  • If no improvement → review for systemic antibiotics, biofilm, or alternative antimicrobial
  • Do not continue silver indefinitely — risk of toxicity and resistance
HHalal Wound Care Products — GCC Consideration
  • Standard collagen dressings may contain porcine (pig-derived) collagen — not halal
  • Request bovine or synthetic collagen alternatives when available
  • Honey dressings: confirm source and processing for Islamic compliance
  • Consult formulary or hospital chaplaincy/ethics for guidance
  • Larvae (maggot) therapy: special religious consideration; discuss with patient and family
Core Principle: Debridement removes devitalised, necrotic, and sloughy tissue that acts as a bacterial culture medium and physically impedes healing. Choose method based on wound type, tissue, patient condition, and nurse competency.

Debridement Methods

SSharp / Surgical Debridement
  • Tools: Scalpel, sharp scissors, curette
  • Speed: Fastest method — immediate removal
  • Indication: Large necrotic burden, urgent debridement, pre-NPWT
  • Competency requirement: Advanced wound care nurse or medical officer; check scope of practice per GCC country/institution
  • Risks: Bleeding, pain (requires local anaesthesia), inadvertent damage to healthy tissue
  • Bedside sharp: Conservative sharp debridement removing only loose devitalised tissue — within trained nurse scope
AAutolytic Debridement
  • Mechanism: Body's own enzymes liquefy devitalised tissue under moist dressing
  • Dressings used: Hydrocolloids, hydrogels, hydrofibres, foams
  • Speed: Slowest method — weeks to months
  • Advantages: Pain-free, selective (only devitalised tissue), suitable for all nurses
  • Contraindication: Infected wounds (autolytic not appropriate as sole method)
  • Best for: Patients unable to tolerate sharp; palliative patients; partial-thickness wounds
EEnzymatic Debridement
  • Agent: Collagenase (Santyl/Iruxol) — selectively digests denatured collagen in slough
  • Application: Apply directly to wound base; cover with non-adherent secondary dressing
  • Frequency: Once daily or every other day
  • Speed: Moderate — faster than autolytic
  • Precautions: Do not use with iodine, silver, or hypochlorite (inactivates enzyme); avoid on clean granulating tissue
  • GCC availability: Check formulary; may require pharmacy procurement
MMechanical Debridement

Wet-to-Dry — NOT Recommended

Historically used; now discouraged — non-selective (damages granulation tissue), painful, promotes infection risk.

Wound Irrigation

Pulsed lavage or syringe irrigation (19G needle/35 ml syringe) at 4–15 psi; removes loose debris and bacteria; use warmed normal saline.

Hydrosurgery (Versajet)

High-pressure water beam simultaneously debrides and irrigates; precise; used in theatre or specialised wound clinic; reduces surgical theatre time.

LLarval Therapy (Maggot Debridement Therapy)
  • Species: Lucilia sericata (green bottle fly) — sterile maggots
  • Mechanism: Secrete proteolytic enzymes (selective); ingest bacteria including MRSA; stimulate healing via growth factors
  • Application: Free-range (loose) or contained (BioBag) larval dressings; changed every 48–72 hours; 100–200 larvae per 10 cm²
  • GCC availability: Limited; sourced from specialist suppliers (UK/Europe); advance ordering required
  • Cultural considerations: Requires detailed informed consent; discuss with patient/family regarding acceptance; consult religious guidance if required
  • Contraindications: Bleeding wounds, wounds near body cavities, dry wounds, unaccepting patient
UUltrasound-Assisted Wound Debridement (UAWD)
  • Low-frequency ultrasound (22.5–40 kHz) delivered via probe or mist
  • Disrupts biofilm, debrides necrotic tissue, stimulates cellular activity
  • Evidence: improves diabetic foot ulcer and chronic wound healing rates
  • Requires specialist device and trained operator; increasing availability in GCC tertiary centres
  • Can be performed at bedside or in wound clinic; generally well-tolerated
🚫
Stable Dry Heel Eschar — DO NOT DEBRIDE: Hard, dry, intact, non-infected eschar on heels acts as a natural protective barrier. Debridement is only indicated if signs of infection develop (erythema, warmth, fluctuance, purulent exudate, or odour). Inspect daily; keep dry.

Selecting the Right Method

Clinical ScenarioRecommended MethodRationale
Large necrotic burden, urgentSharp/surgicalSpeed; improves NPWT uptake
Dry, non-infected necrosisAutolytic (hydrogel)Safe, rehydrates, selective
Sloughy, low infection riskAutolytic or enzymaticSelective removal
Infected, heavy biofilmSharp + antimicrobial dressingRemoves biofilm; addresses infection
MRSA-colonised diabetic footLarval therapy or UAWD + silverSelective; anti-biofilm
Frail/palliative patientAutolytic onlyComfort; minimise pain

Pressure Injuries — NPIAP Classification 2019

StageDescriptionClinical FeaturesManagement
Stage 1Non-blanchable erythemaIntact skin; localised redness; may differ in darkly pigmented skin (darker/purple tone)Offload immediately; barrier cream; reposition 2-hourly; SSKIN bundle
Stage 2Partial thicknessOpen shallow wound or intact/ruptured blister; red-pink wound bed; no slough/escharMoist healing; foam or hydrocolloid; offloading; nutrition review
Stage 3Full thickness skin lossVisible subcutaneous fat; slough may be present; undermining/tunnelling possible; no bone/muscle/tendon visibleDebridement; NPWT for cavities; nutrition; offloading; specialist review
Stage 4Full thickness tissue lossExposed bone/muscle/tendon/cartilage; slough/eschar; often undermining/tunnellingSurgical referral; NPWT; osteomyelitis workup; nutritional support; MDT approach
UnstageableDepth unknownFull thickness but covered by slough/eschar; depth cannot be determined until debridedDebride (except dry stable heel eschar); reassess stage post-debridement
Deep Tissue InjuryDTI — suspectedIntact/non-intact skin with deep purple/maroon localised area or blood-filled blister; rapid deterioration possibleImmediate full offloading; monitor closely; may evolve to Stage 3/4 within days
SSSKIN Bundle — Pressure Injury Prevention
S
Surface
Appropriate pressure-redistributing mattress/cushion; bariatric equipment for obese patients
S
Skin Inspection
Inspect all bony prominences every shift; use lighting adequate for darker skin tones
K
Keep Moving
Reposition every 2 hours (chair: 15 min); use repositioning aids; document turns
I
Incontinence
Prompt cleansing; moisture barriers; incontinence-associated dermatitis (IAD) prevention
N
Nutrition
Nutritional screening (MUST); dietitian referral; protein 1.2–1.5 g/kg/day; Vitamin C/Zinc supplementation

Leg Ulcers — Arterial vs Venous

VVenous Leg Ulcers
  • Location: Gaiter region (medial malleolus most common)
  • ABI requirement: Doppler ABPI >0.8 before applying compression
  • Compression: 4-layer high-compression bandaging (40 mmHg at ankle); sustain 2–3 weeks before reassessment
  • After healing: Compression hosiery (Class 2–3) for life to prevent recurrence
  • Wound care: Moist healing; manage heavy exudate (alginate/hydrofibre under compression)
  • Lipodermatosclerosis: Induration/fibrosis — does not indicate infection; continue compression
Never apply compression without Doppler ABPI assessment — risk of ischaemic limb loss.
AArterial Leg Ulcers
  • Location: Distal/dorsum of foot, toes, pressure points
  • ABI <0.6: Severe ischaemia — NO COMPRESSION; urgent vascular referral
  • ABI 0.6–0.8: Mixed arterial/venous — reduced compression only under vascular specialist guidance
  • Features: Punched-out, pale/necrotic base; minimal exudate; painful (worse at night/elevation); hair loss; cool limb; absent pulses
  • Wound care: Keep dry if ischaemic; non-adherent dressings; do NOT debride without vascular assessment
  • GCC context: High peripheral arterial disease burden associated with diabetes prevalence

Diabetic Foot Wounds

DIWGDF Classification & Key Management

IWGDF Wound Classification

  • Grade 0: No open wound; high risk foot
  • Grade 1: Superficial wound; no infection/ischaemia
  • Grade 2: Deep wound; tendon/capsule/bone involvement
  • Grade 3: Osteomyelitis / abscess / fasciitis
  • Grade 4: Localised gangrene (toe/forefoot)
  • Grade 5: Extensive gangrene — amputation risk

Key Management Principles

1Offloading — Total Contact Cast (TCC) gold standard; half-shell / removable cast walker; reduce plantar pressure by 30–50%
2Weekly debridement — sharp debridement of callus and non-viable tissue at every appointment
3Infection: Systemic antibiotics for clinical infection ONLY — not for colonisation; culture-guided therapy
4Vascular status: ABI/TBI assessment; revascularisation if indicated before expecting wound healing
5Osteomyelitis: X-ray (sensitivity low); MRI gold standard; probe-to-bone test positive = high suspicion

Dehisced Surgical Wounds

WManagement Decision Framework

Secondary Intention Healing

  • Most dehisced wounds heal by secondary intention (granulation → contraction → epithelialisation)
  • Wound packing: non-traumatic (alginate ribbon, hydrofibre rope) for deep cavities
  • NPWT: consider for large cavities, high exudate, or to accelerate granulation
  • Assess daily for infection signs; culture if purulent exudate develops

Re-closure Considerations

  • Re-closure (tertiary/delayed primary) considered if: wound is clean/infection-free, good tissue quality, patient stable
  • Surgical decision; nurse role: optimise wound bed pre-closure
  • Document size, depth, tissue type, exudate at every dressing change
  • Refer to surgical team if wound stalling, exposed mesh/implant, or fistula formation

Wound Infection Continuum

Contamination
Microbes present; no replication; no host response
Colonisation
Replication; no host response; no treatment needed
!
Critical Colonisation
Increased burden; biofilm; subtle wound signs; stalling
!!
Local Infection
NERDS/STONEES signs; confined to wound
!!!
Spreading Infection
Cellulitis; lymphangitis; systemic antibiotics
🚨
Systemic Sepsis
SIRS criteria; ICU; IV antibiotics; emergency
NNERDS — Superficial Wound Infection
N
Non-healing
E
Exudate ↑
R
Red Friable
D
Debris
S
Smell

≥3 NERDS criteria: treat with topical antimicrobial (silver/honey/iodine dressing). No systemic antibiotics required at this stage.

SSTONEES — Deep / Spreading Wound Infection
S
Size increase
T
Temperature ↑
O
Os (probe to bone)
N
New breakdown
E
Erythema/Oedema
E
Exudate
S
Smell

≥3 STONEES criteria: systemic antibiotics + urgent medical review. Wound swab + blood cultures if systemic signs.

Wound Swab Technique — Levine Method

1Clean wound with sterile normal saline and allow to dry briefly (removes surface contaminants)
2Moisten swab tip with sterile normal saline (prevents drying out of sample)
3Select representative 1 cm² area of wound bed (avoid necrotic tissue, sinus tracts unless specifically requested)
4Apply firm pressure and rotate swab 5–10 seconds in zigzag pattern across 1 cm² (Levine method ensures fluid expressed from wound tissue)
5Place in appropriate transport medium immediately; label with patient details, wound site, date/time, clinical information
6Transport to lab within 2 hours; refrigerate if delay anticipated; document antibiotic therapy on form
Swab surface bacteria ≠ causative organism. Tissue biopsy is gold standard if osteomyelitis or deep infection suspected. Levine swab acceptable for most clinical practice.

Systemic Antibiotic Indications

!Indications (Prescribe Systemic Antibiotics)
  • Spreading cellulitis (>2 cm erythema from wound edge with warmth and tenderness)
  • Lymphangitis (red streaks tracking from wound)
  • Systemic sepsis (fever/hypothermia, tachycardia, hypotension, altered consciousness)
  • Osteomyelitis (confirmed or strongly suspected)
  • Necrotising fasciitis (EMERGENCY)
  • Diabetic foot infection grade 2+ (IWGDF)
NOT Indications (Avoid Systemic Antibiotics)
  • Wound colonisation alone (no clinical infection signs)
  • Critical colonisation — use topical antimicrobial first
  • Wound odour alone without other infection criteria
  • Prophylaxis for chronic non-healing wounds
  • Purulent exudate without systemic signs in clean wounds — treat locally first
🚨
NECROTISING FASCIITIS — SURGICAL EMERGENCY
Early signs: Severe disproportionate pain, rapidly spreading erythema, skin discolouration (grey/dark), systemic toxicity, fever.
Late signs (DO NOT WAIT FOR THESE): Skin anaesthesia over affected area (nerve death), crepitus (gas in tissue), woody-hard induration, skin necrosis/bullae.
Action: CALL SURGICAL TEAM IMMEDIATELY. IV access + broad-spectrum antibiotics + IV fluids + surgical debridement within hours (delay = mortality). LRINEC score >6 suggests high risk.

GCC-Specific Wound Care Considerations

DDiabetic Foot — GCC Epidemic
  • GCC nations have the highest diabetes prevalence globally (Saudi Arabia ~18%, UAE ~17%, Kuwait ~25% estimates)
  • Diabetic foot complications are the leading cause of non-traumatic lower limb amputation in the region
  • Early screening: annual diabetic foot exam for all patients with DM ≥5 years
  • Dedicated diabetic foot clinics operational in most major GCC tertiary hospitals
  • Cultural factors: delayed presentation due to denial, reliance on traditional remedies (zaatar, honey, henna packs — document and educate)
  • Ramadan fasting: altered insulin regimens; monitor foot wounds closely during fasting period
THeat & Wound Healing in GCC Climate
  • Extreme heat (summer temperatures 45–50°C) → poor microcirculation, increased bacterial proliferation
  • Outdoor workers (construction, agriculture) at high risk: dehydration impairs wound healing
  • Encourage wound site protection from direct sun and heat
  • Dressings may loosen faster in humid/sweating conditions — consider waterproof/silicone-bordered options
  • Advise patients to avoid applying traditional heat treatments (warm cloth, sand) to wounds
  • Sand contamination: common in Hajj pilgrims and outdoor workers — thorough irrigation essential
CCultural Factors in GCC Wound Care
  • Modesty: Female patients should be attended by female nurses for wound care wherever possible; communicate proactively about staffing
  • Wound photography: Obtain explicit written consent; some patients object for religious or cultural reasons; document refusal and describe wound in detail as alternative
  • Informed consent: Discuss wound care procedures with patient and (often) family — family involvement in decision-making is culturally normative
  • Arabic-language education: Use validated Arabic wound care patient education materials; avoid relying solely on English; many hospitals provide bilingual wound care leaflets
  • Traditional remedies: Ask about use of honey, henna, herb poultices — document and educate on evidence-based alternatives without dismissing culture
BPressure Injuries in Obese GCC Patients
  • Rising obesity rates (30–40% of adult GCC population) increase pressure injury risk
  • Bariatric equipment: Ensure mattresses/beds rated for patient weight (standard mattresses often max 120–150 kg)
  • Moisture in skin folds: intertrigo, fungal infection — inspect and treat skin folds routinely
  • Specialised bariatric cushions with higher foam density for wheelchair-dependent patients
  • Repositioning: requires additional staff for safe moving; document manual handling risk assessment
  • Heel elevation: pillow placement under calf (not heel) in high-risk obese patients

Halal & Formulary Considerations

Halal Wound Care Products

  • Porcine (pig-derived) collagen dressings not permissible under Islamic law — request bovine or synthetic collagen
  • Porcine gelatin in some wound care formulations — check product SPC
  • Medical-grade honey is generally considered permissible; confirm source
  • Larval therapy: seek religious guidance; some scholars permit due to medical necessity (darura)
  • Consult hospital pharmacy and chaplaincy service; document in care plan

GCC Formulary Availability

  • Advanced wound care products available in major GCC hospitals but formulary varies by institution and country
  • NPWT devices widely available in tertiary centres (Saudi Arabia, UAE, Qatar)
  • Larval therapy: limited; requires specialist procurement from UK/Europe
  • Biologics and advanced cellular therapies: increasing availability in academic centres
  • Generic equivalents often available — verify bioequivalence and handling requirements
  • Obtain procurement approval in advance for non-formulary items

GCC Wound Care Nursing Certification

CSpecialist Certification Pathways

International Certifications Recognised in GCC

  • CWOCN (Certified Wound Ostomy Continence Nurse) — WOCNCB, USA; widely recognised by GCC MOH
  • CWCN (Certified Wound Care Nurse) — entry-level wound specialty
  • FWCS (Fellow Wound Care Specialist) — advanced practice
  • ETRS/EWMA European wound care certifications — accepted in some GCC institutions

GCC-Based Wound Care Education

  • Saudi Commission for Health Specialties (SCFHS) — wound care modules
  • Dubai Health Authority (DHA) and HAAD (Abu Dhabi) wound care CPD programmes
  • Hamad Medical Corporation (Qatar) wound care specialist pathway
  • Annual GCC wound care conferences (SWCA, MENA wound care forums)
  • Arabic-language wound care training resources increasingly available

Hajj & Mass Gathering Wound Considerations

HHajj Pilgrimage — Wound Care Challenges

Interactive Wound Assessment & Dressing Selector

Enter wound parameters below to receive evidence-based dressing recommendations, change frequency, and clinical alerts.

Primary Dressing Recommendation
Specific Products (Examples)
Change Frequency
Debridement Recommendation
Periwound Skin Care
Special Precautions & Escalation