<150
P/F Ratio Threshold (mmHg) to indicate proning
16h
Minimum daily prone duration (PROSEVA protocol)
16%
28-day mortality — prone group (vs 32.8% supine)
NNT 6
Number Needed to Treat to prevent 1 death
50%
Relative mortality reduction (PROSEVA 2013)
📊PROSEVA Trial (2013) — Landmark Evidence
Guerin C et al. NEJM 2013 — The Definitive Trial
466 patients with severe ARDS (P/F <150 on PEEP ≥5, FiO2 ≥0.6). Randomised to proning ≥16h/day vs supine. 28-day mortality: 16% (prone) vs 32.8% (supine) — p<0.001. This is now the standard of care for moderate-severe ARDS.
Trial Design
- Population: Severe ARDS within 36h of diagnosis
- Criteria: P/F <150, PEEP ≥5 cmH2O, FiO2 ≥0.6
- Intervention: Proning ≥16h/day until improvement
- Control: Semirecumbent supine position
- Primary outcome: 28-day all-cause mortality
- Setting: 26 ICUs in France and Spain
Key Results
- 28-day mortality: 16% vs 32.8% (p<0.001)
- 90-day mortality: 23.6% vs 41% (p<0.001)
- NNT: 6 patients to prevent 1 death
- P/F improvement: Significant within 4h
- No increase in adverse events
- Ventilator-free days: Improved in prone group
✓Indications for Proning
All 3 criteria must be met
- P/F ratio <150 mmHg on current ventilator settings
- PEEP ≥5 cmH2O and FiO2 ≥0.6
- Criteria present for >12 hours despite optimised conventional ventilation
- No absolute contraindications present
- Lung-protective ventilation already in place (TV 6 mL/kg IBW, Pplat <30)
ARDS Severity Classification (Berlin)
Mild: P/F 200–300 | Moderate: P/F 100–200 | Severe: P/F <100. Proning indicated for moderate-severe (P/F <150).
!Contraindications
| Contraindication | Type |
| Spinal instability / unstabilised fractures | Absolute |
| Open chest / sternotomy | Absolute |
| Severe facial / cranial fractures | Absolute |
| Recent tracheal surgery (<2 weeks) | Absolute |
| Raised intracranial pressure (>30 mmHg) | Absolute |
| Haemodynamic instability on high vasopressors | Relative |
| Morbid obesity (BMI >35) | Relative |
| Pregnancy (>20 weeks) | Relative |
| Massive anterior burns | Relative |
| Recent anterior abdominal surgery | Relative |
⚙Mechanisms of Benefit
Ventilation Homogeneity
- In supine ARDS, posterior (dependent) lung is collapsed/flooded
- Prone redistributes ventilation more evenly
- Reduces dorsal-to-ventral transpulmonary pressure gradient
- Recruits previously dependent collapsed alveoli
Reduced VILI
- Decreases cyclic atelectasis in dependent zones
- Reduces stress concentration at aerated-consolidated boundaries
- More homogeneous tidal volume distribution
- Lowers driving pressure requirements
Other Benefits
- Improved secretion clearance (gravitational drainage)
- Cardiac output may improve (reduced lung compression of heart)
- Reduced V/Q mismatch
- Improved FRC (functional residual capacity)
Safety First: Never rush a prone turn.
Preparation is the most critical phase. A poorly prepared prone turn risks ETT dislodgement, line disconnection, haemodynamic collapse, and severe pressure injuries. Allow 20–30 minutes for complete preparation.
👥Team Assembly — Minimum 5 Personnel
Each team member must know their role BEFORE the turn begins. Verbal briefing is mandatory.
| Role | Position | Responsibilities |
| Airway Nurse (Team Leader) |
Head of bed |
Controls ETT throughout turn, leads the count, calls halt if problem, does not let go of airway |
| Lateral Nurse 1 |
Right side of patient |
Controls right shoulder and hip, manages right-side lines |
| Lateral Nurse 2 |
Left side of patient |
Controls left shoulder and hip, manages left-side lines |
| Foot Nurse |
End of bed |
Controls legs and feet, manages urinary catheter and lower extremity lines |
| Coordinator / Runner |
Free movement |
Manages ventilator, monitors, calls out vitals, fetches equipment, documents time |
🛏Equipment Preparation
Positioning Pads (Anatomical Landmarks)
- Forehead pad: Silicone foam — above eyes, allows face to hang free
- Chest pad: Bilateral — clavicles to ASIS, allows abdomen to hang freely
- Pelvic pad: Bilateral — anterior superior iliac spine (ASIS) to upper thigh
- Knee pads: Bilateral — foam beneath patella
- Foot/toe pad: Beneath dorsum of feet to prevent foot drop
Abdomen MUST hang freely — this is essential for diaphragm excursion and cardiac output benefit. Chest and pelvic pads must not meet in the middle.
Pressure Injury Prevention
- Silicone foam dressings: forehead, chin, nose, cheeks
- Additional foam: chest bony prominences, patellae
- Hydrocolloid on ears if prolonged proning planned
- Male patients: protect genitalia with soft padding
🔗Lines, Tubes & Airway Security
ETT Security
- Re-tape/re-secure ETT with additional adhesive tape
- Confirm and document ETT cm marking at lips/teeth
- Confirm ETT position by auscultation before turn
- Suction ETT before turn to clear secretions
- Note ETCO2 waveform baseline
All Lines & Drains
- Label all IV lines and invasive monitoring lines clearly
- Ensure sufficient line length for 180° turn
- Clamp chest drains temporarily during turn (re-open immediately after)
- Clamp NG/gastric tube temporarily; drain/aspirate gastric contents before turn
- Secure urinary catheter to avoid traction
- Identify route for each line — plan which side it will exit
- Remove unnecessary attachments before turn
Eye Care
- Instil lubricating eye drops bilaterally
- Apply eye gel (Lacrilube or equivalent)
- Tape eyelids closed with micropore/paper tape
- Corneal abrasion risk is high in prone — eyes must be protected every cycle
Gastric Preparation
- Aspirate gastric tube and document volume
- Hold enteral feeds 30 min before turn
- Consider metoclopramide prophylactically
📋Pre-Prone Briefing Checklist
The team leader (airway nurse) should verbally run through this briefing with all team members. Each person confirms their role before the turn begins. Use the interactive checklist in the tool tab.
- All 5 team members present and role-assigned
- ETT secured with extra tape, cm mark confirmed
- All pads prepared and at bedside
- Silicone foam dressings on face
- Eyes lubricated and taped
- Gastric aspirated, feeds held
- All IV lines labelled and length confirmed
- Drainage bags clamped (ready to release)
- Contraindications excluded and documented
- Consent (if awake) or next-of-kin informed
- Ventilator FiO2 temporarily increased to 1.0
- Time and date documented — prone start time
Airway nurse LEADS and CONTROLS the count. No one moves until the count of 3.
The airway nurse is the only person who can call "STOP" during the turn if there is a problem with the ETT or patient haemodynamics.
▶Prone Turn — Step-by-Step Procedure (180° Rotation)
-
Increase FiO2 to 1.0 — pre-oxygenate for 3–5 minutes before initiating the turn. Confirm SpO2 stable.
-
Slide patient to the turning side rail — move patient laterally towards the direction of the first turn (typically right side). Ensures space to complete the 180° rotation without falling off the bed.
-
Cross the far arm — the arm on the side being turned toward goes across the body (under the patient's torso) to assist the rotation. The near arm stays alongside or is placed up by the head (swimmer position).
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All team members take positions — airway nurse at head (hands on ETT and head), lateral nurses on sides, foot nurse at feet. Coordinator stands back to manage ventilator and monitor.
-
Final check and verbal confirmation — airway nurse asks: "Is everyone ready?" Each person verbally confirms. Lines checked clear. Airway nurse confirms ETT position at lips.
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Turn onto side (90°) on count of 3 — "1, 2, 3, TURN" — smooth coordinated lateral rotation. Patient is now in lateral decubitus. PAUSE and reassess: SpO2, ETT, BP.
-
Complete rotation to prone (180°) — on second count from airway nurse: roll patient fully prone in one smooth, coordinated motion. Airway nurse rotates head simultaneously — head turns last to complete the rotation.
-
Position head in anatomical neutral — forehead on pad, slight lateral rotation (to one side), ensure face not flattened. Neck in neutral — not hyperextended or laterally rotated beyond comfort.
-
Arms — swimmer position or alongside body — Swimmer: one arm up (elbow flexed, hand near head), one arm down alongside body. Alternate arm position every 2 hours. Ensure no brachial plexus stretch.
-
Place chest and pelvic pads — bilateral chest pads from clavicles to ASIS. Bilateral pelvic pads from ASIS to upper thigh. Confirm abdomen hangs freely between pads — this is essential.
-
Knee and toe pads positioned — foam beneath patellae bilaterally. Dorsal foot pads to maintain ankle in neutral (prevent foot drop). Toes must not bear weight.
-
Reconnect all monitoring — SpO2 probe to finger/ear, ECG leads repositioned on back, arterial line transducer zeroed, central line infusions confirmed running.
-
Confirm ETT position — bilateral auscultation of chest, confirm ETCO2 waveform, note cm mark at lips unchanged. If any doubt — CXR.
-
Reduce FiO2 back to previous setting — after confirming SpO2 stable. Adjust ventilator as needed (PEEP may need fine-tuning).
-
Document prone start time — exact time, team members present, any events during turn, ETT cm mark, initial post-prone SpO2 and BP.
⚠If Desaturation During Turn
- Call STOP — airway nurse calls halt immediately
- Return to supine if SpO2 <85% and not recovering
- Check ETT — listen bilaterally, confirm ETCO2
- Increase FiO2 to 1.0
- Manual ventilation if needed
- If SpO2 recovers with position — can attempt turn again after stabilisation
- Document the event in safety log
!If ETT Dislodgement Suspected
STOP the turn immediately. Do not complete the rotation.
- Airway nurse holds ETT — do not release
- Return patient to supine immediately
- Confirm ETT position by auscultation and ETCO2
- If confirmed displaced — follow emergency reintubation protocol
- Notify medical team immediately
- Complete incident report
- Proning can be reattempted once ETT confirmed and patient stabilised
First 2 hours after proning require intensified monitoring.
Physiological response (P/F improvement) is expected within 1–4 hours. If no improvement by 4 hours, escalate to medical team and reassess.
♥Vital Signs
Frequency
- First 1–2 hours: HR and BP every 15 min
- After 2 hours: Hourly if stable
- Continuous: SpO2 and ECG monitoring
Expected Changes
- SpO2 may transiently drop during turn — should recover within 30 min
- BP may fluctuate with position — if MAP drops >20% escalate
- HR often decreases as oxygenation improves
🫁Ventilator Parameters
- Check P/F ratio at 1, 2, and 4 hours post-turn
- Expect PaO2/FiO2 improvement within 1–4h in responders
- Peak and plateau pressure — compliance may improve
- PEEP — may need minor adjustments
- Tidal volume — maintain 6 mL/kg IBW (lung-protective)
- ETCO2 waveform — confirm continuous and normal morphology
Non-responders (no P/F improvement at 4h): Notify medical team. Consider: ETT malposition, secretion plugging, pneumothorax, positioning issue.
🫀Arrhythmia Monitoring
- ECG electrodes repositioned on posterior chest after proning
- Continuous cardiac monitoring mandatory
- Position-related bradycardia — usually transient
- Ventricular ectopy may occur with myocardial stretch
- AF can be triggered or worsened
- Notify medical team for any sustained arrhythmia
- Defibrillation possible in prone — use anterior/posterior pads
🩹Pressure Injury Surveillance (2-Hourly)
Face and body must be checked every 2 hours during proning. Pad repositioning at every check.
Face — 2-Hourly Check
- Forehead — foam pad pressure, blanching?
- Nose — tip and bridge (high risk)
- Chin — contact with pad or bed?
- Cheeks — bilateral assessment
- Ears — especially the dependent ear
- Alternate head position (left/right lateral) every 2 hours
Body — 2-Hourly Check
- Chest — clavicles and anterior ribs
- Knees — bilateral, reposition knee pads
- Toes and dorsum of feet
- Male genitalia — ensure no pressure
- Grade any lesion using EPUAP/NPUAP scale and document
👁Eye Protection & ETT Care
Eye Monitoring
- Check eye closure hourly — tape must remain intact
- Re-apply eye gel if tape loosens
- Confirm no direct pressure on eyeballs from pad
- Check for chemosis (conjunctival oedema) — document
- Ophthalmology review if any concern on return to supine
ETT Monitoring
- Check ETT cm mark at lips/teeth every 2 hours
- Listen for bilateral air entry at each check
- Suction as needed — prone improves secretion mobilisation
- Expect increased secretion volume (gravitational drainage benefit)
- Note secretion character: colour, consistency, volume
Enteral Nutrition During Proning
- Continue EN at reduced rate 20–40 mL/hr
- Check GRV (gastric residual volume) every 4 hours
- Hold if GRV >200 mL — recheck in 2h
- Elevated head of bed not possible in prone — aspiration risk managed by rate reduction
- Ensure NGT patent; flush every 4h
↩Supination Criteria — When to Return to Supine
Standard Supination (Planned)
- Minimum 16 hours of prone positioning completed
- SpO2 stable on current ventilator settings
- 5-person team available and prepared
- Scheduled as part of daily weaning assessment
- Medical team aware and agreed
Emergency Supination (Unplanned)
- Cardiac arrest — return to supine immediately
- ETT dislodgement requiring reintubation
- SpO2 <85% unresponsive to FiO2 increase
- Haemodynamic collapse (MAP <50 unresponsive)
- Life-threatening arrhythmia
- Document reason and prone duration achieved
▶Supination Procedure
Same 5-person team, same roles, reverse procedure. Airway nurse leads the count and controls the head. FiO2 increased to 1.0 before turning.
- Pre-supination preparation: Increase FiO2 to 1.0. Team in position. Verbal briefing. Confirm ETT cm mark. Remove face and body pressure dressings for inspection.
- Reposition cross-arm: Place the arm for rotation across body as per proning preparation.
- Slide to side rail: Move patient to side of bed in direction of rotation.
- Coordinated 180° turn on count of 3: Airway nurse leads — same smooth rotation. Lateral and foot nurses coordinate.
- Return to semi-recumbent supine: Aim 30–45° head-of-bed elevation to reduce VAP risk once stable.
- Confirm ETT position: Bilateral auscultation + ETCO2 waveform. If cm mark changed — reassess and CXR if concern.
- Reconnect all monitoring: ECG leads to anterior chest, SpO2, arterial transducer zeroed, infusions confirmed.
- Document supination time and actual prone duration.
🔍Post-Supination Assessment
Haemodynamic Response (First 30–60 min)
- BP and HR every 15 min for first hour
- May transiently desaturate — usually self-resolves
- May transiently drop BP — if persistent, notify medical team
- P/F ratio benefit can persist 4–12h post-supination in responders
- If P/F deteriorates significantly — consider re-proning
Pressure Injury Inspection
- Full face assessment — forehead, nose, chin, cheeks, ears
- Grade all lesions using EPUAP/NPUAP scale
- Photograph and document all findings
- Chest wall, knees, dorsal feet
- Wound management team referral if grade 2+
🔄Repeat Proning & Ventilator Management
Repeat Proning Criteria
- Can repeat daily 16h cycles if P/F still <150 on return
- Typically 1–4 cycles in first week of ARDS
- Same indications and contraindications apply
- Stop cycling when P/F >150 on PEEP ≤10 and FiO2 ≤0.6 (improved)
Ventilator Adjustments Post-Supination
- PEEP may need to be increased if oxygenation deteriorates
- Recruitment manoeuvre may help post-supination atelectasis
- Continue lung-protective ventilation (TV 6 mL/kg IBW)
- Consider spontaneous breathing trials when P/F improves and PEEP ≤8
- FiO2 should be reduced as oxygenation improves — titrate to SpO2 92–95%
Eye Assessment on Return to Supine
Remove eye tape carefully. Assess for corneal abrasion (pain, photophobia, fluorescein staining). Ophthalmology referral if suspected. Continue lubricating drops and taping if proning will be repeated.
🏥COVID-19 ARDS Proning in GCC (2020–2022)
- Major proning volumes across GCC ICUs during COVID-19 pandemic
- Saudi Arabia, UAE, Qatar, Kuwait, Bahrain, Oman — all developed institutional prone protocols 2020
- Significant nursing expertise built during pandemic waves
- Many centres ran prone teams 24/7 during peak ICU occupancy
- Nurses trained in both intubated and awake prone positioning
- Simulation-based proning training became standard in tertiary centres
- Multi-language patient instructions developed including Arabic
Awake Proning (Non-Intubated) — Arabic Instructions
"تقدر تتقلّب على بطنك؟"
"نحتاج منك تنام على بطنك لتحسين تنفسك."
"هذا الوضع يساعد رئتيك."
"Can you roll onto your tummy?" | "We need you to lie on your stomach to improve your breathing." | "This position helps your lungs."
⚠High Obesity Prevalence in GCC — Technical Challenges
GCC has some of the world's highest obesity rates (BMI >30: 35–40% of adults in some GCC states)
- BMI >35: Relative contraindication — requires senior decision and additional planning
- Extra staff: Consider 6–7 personnel for obese patients
- Bariatric beds: Wider turning space essential; standard beds may be inadequate
- Additional foam pads: Larger body surface requires more padding at more points
- Abdominal decompression: Critical — abdomen must hang freely; harder to achieve in morbid obesity
- Tracheostomy consideration: For prolonged ARDS in obese patients — improves airway security during repeated turns
- Increased pressure injury risk: More surface contact area — check every 1–2h
- Line management: More difficult to access lines in deep tissue
🦠MERS-CoV ARDS in GCC
- Middle East Respiratory Syndrome — endemic to Arabian Peninsula
- MERS-CoV ARDS has high case fatality rate (35–40%)
- GCC ICUs have most experience globally with MERS-CoV critical care
- Proning protocols adapted for MERS — full PPE required during prone turns
- Aerosol-generating procedure protocols for prone turns in MERS patients
- Saudi Arabia developed MERS ICU protocols referenced internationally
- Camels as zoonotic reservoir — episodic outbreaks continue in KSA
📚GCC Proning Programmes & Training
- Simulation-based team training: Standard in tertiary GCC centres (King Faisal Specialist, Cleveland Clinic Abu Dhabi, Hamad Medical Corporation, etc.)
- Prone teams: Designated trained prone teams in most GCC tertiary ICUs
- Competency assessment: Annual prone positioning competency for ICU nurses
- Multi-language protocols: Arabic, English, Tagalog, Hindi — reflecting GCC ICU nursing workforce diversity
- Safety reporting: Proning incidents reported through institutional adverse event systems (e.g., CERNER, Epic safety reporting modules)
- National guidelines: SCCC (Saudi Critical Care), ESICM guidelines used across GCC
📋Documentation & Safety Reporting for Prone Episodes in GCC
Mandatory Documentation
- Prone start and end time (calculate duration)
- Team members present (names and roles)
- Pre-prone and post-prone P/F ratio
- ETT cm mark before/after
- Pressure injury findings — each body region
- Any events during turn
Reportable Incidents
- ETT dislodgement or change in position
- Accidental extubation
- Line disconnection / medication interruption
- Cardiac arrest during turn
- New pressure injury grade 2 or above
- Corneal abrasion confirmed
Quality Metrics
- Prone duration achieved vs target (≥16h)
- % patients receiving proning who met criteria
- Pressure injury incidence per prone episode
- ETT dislodgement rate per 100 prone turns
- P/F ratio response at 4h (responder rate)
- 28-day mortality in ARDS patients proned