Definition
A pressure injury is localised damage to the skin and/or underlying soft tissue, usually over a bony prominence or related to a medical or other device. The injury can present as intact skin or an open ulcer and may be painful. It occurs as a result of intense and/or prolonged pressure or pressure in combination with shear.
NPIAPEPUAPPPPIA 2019 Guidelines
Pathophysiology
Primary Mechanical Forces
- Pressure: perpendicular force compressing capillaries (normal capillary pressure ~32 mmHg) — prolonged occlusion → ischaemia
- Shear: parallel forces causing blood vessels to stretch/kink — particularly dangerous at sacrum when HOB elevated
- Friction: surface abrasion damaging the epidermis — dragging patient up bed
- Moisture: maceration weakens skin barrier integrity — incontinence/perspiration
Pathological Cascade
- Capillary occlusion → tissue ischaemia (as little as 2 hours)
- Ischaemia → reperfusion injury (reactive oxygen species on pressure relief)
- Cell necrosis begins in deeper muscle before skin surface damage is visible
- Inflammatory mediators → oedema → further impaired perfusion
- Deep Tissue Pressure Injury can appear deceptively mild on surface
NPIAP Classification Staging System
Stage 1 — Non-Blanchable Erythema
Intact skin with non-blanchable redness. Skin may be painful, firm, soft, warmer or cooler. Difficult to detect in darker skin tones — assess by warmth, firmness, pain.
Intact SkinStage 2 — Partial Thickness
Partial thickness skin loss with exposed dermis. Wound bed is pink/red, moist. May present as intact or ruptured blister. Adipose not visible. No slough/eschar.
Open Shallow / BlisterStage 3 — Full Thickness Skin Loss
Full thickness skin loss — subcutaneous fat may be visible. Granulation tissue and rolled wound edges often present. Slough/eschar may be present. Depth varies by location.
Subcutaneous Fat VisibleStage 4 — Full Thickness Tissue Loss
Full thickness skin and tissue loss with exposed or directly palpable fascia, muscle, tendon, ligament, cartilage or bone. Slough/eschar may be present. Undermining/tunnelling common.
Bone/Tendon/Muscle VisibleUnstageable
Full thickness skin and tissue loss — depth obscured by slough (yellow/tan/grey) or eschar (tan/brown/black) covering wound base. Cannot stage until base is visible — debridement required.
Slough/Eschar Covers BaseDeep Tissue Pressure Injury (DTPI)
Intact or non-intact skin with localised area of persistent deep red, maroon or purple discolouration, or epidermal separation revealing dark wound bed. May evolve rapidly to Stage 3/4. Often more extensive than it appears.
Rapid Deterioration RiskDevice-Related Pressure Injury (DRPI)
Results from use of a medical or other device. Injury generally conforms to the pattern/shape of the device. Should be staged using the standard NPIAP staging system.
- Oxygen masks/nasal cannulae
- Endotracheal tube holders/tapes
- Nasogastric tubes
- Urinary catheters
- Cervical collars, splints, casts
- Sequential compression devices
Mucosal Membrane Pressure Injury
Found on mucous membranes with a history of a medical device in use at the location of the injury. Due to the anatomy of the tissue, these injuries cannot be staged.
- Oral mucosa — ETT/bite blocks
- Nasal mucosa — NG/nasotracheal tubes
- Urethral mucosa — urinary catheters
Braden Scale — Pressure Injury Risk Assessment
The Braden Scale is the most widely validated pressure injury risk tool. It assesses 6 domains with subscores. Lower total score = higher risk.
| Domain | 1 — Most Impaired | 2 | 3 | 4 — Least Impaired |
|---|---|---|---|---|
| Sensory Perception Ability to respond to pressure-related discomfort | Completely limited | Very limited | Slightly limited | No impairment |
| Moisture Degree skin exposed to moisture | Constantly moist | Very moist | Occasionally moist | Rarely moist |
| Activity Degree of physical activity | Bedfast | Chairfast | Walks occasionally | Walks frequently |
| Mobility Ability to change/control body position | Completely immobile | Very limited | Slightly limited | No limitations |
| Nutrition Usual food intake pattern | Very poor | Probably inadequate | Adequate | Excellent |
| Friction & Shear Scored 1–3 only | Problem | Potential problem | No apparent problem | — |
Very High Risk
≤9
Hourly repositioning; highest specification mattress; intensive monitoring
High Risk
10–12
2-hourly repositioning; alternating pressure mattress; full SSKIN bundle
Moderate Risk
13–14
2–3 hourly repositioning; pressure-redistributing mattress; SSKIN bundle
Mild Risk
15–18
3–4 hourly repositioning; standard mattress + foam overlay; routine monitoring
No Risk
19–23
No specific pressure care required; preventive education only
Waterlow Score
Widely used in the UK and GCC (particularly in hospitals following NHS/JCI protocols). Unlike Braden, higher Waterlow score = higher risk.
Risk Thresholds
- At Risk: 10–14
- High Risk: 15–19
- Very High Risk: 20+
Domains Assessed
- Build/weight for height (BMI)
- Skin type / visual risk areas
- Sex and age
- Continence
- Mobility
- Appetite/nutritional risk (MUST)
- Special risks: tissue malnutrition / neurological deficit / surgery / medication
Assessment Frequency
- On admission — within 6 hours (JCI standard)
- Re-assess daily for high/very high risk patients
- Re-assess every 3 days for moderate risk
- Re-assess on every clinical change (surgery, deterioration, new device)
- Document score and date/time in patient record
High-Risk Patient Categories
Critical Care
- ICU/HDU patients on vasopressors
- Mechanically ventilated (prone positioning risk)
- Sedated/paralysed patients
- Multiple medical devices
Neurological
- Spinal cord injury
- Stroke with hemiplegia
- Diabetic peripheral neuropathy
- Sedated/anaesthetised patients
Systemic
- Malnutrition / cachexia (BMI <18.5)
- Oedema (poor tissue perfusion)
- Peripheral vascular disease
- Diabetes mellitus
Contextual
- Elderly / frail patients
- Faecal and/or urinary incontinence
- Post-operative patients
- Prolonged theatre time (>4 hrs)
Never Events
- Category 3, 4 and DTPI acquired in hospital are reportable
- Mandatory DATIX/incident report
- Root cause analysis required
- Reportable to CQC/DHA/JCI
SSKIN Bundle Overview
S — Surface
Appropriate pressure-redistributing mattress based on risk score
S — Skin Inspection
Regular systematic skin inspection at each repositioning
K — Keep Moving
Scheduled repositioning programme with documented chart
I — Incontinence
Structured skin care regime: barrier cream, moisture wipes, SICP
N — Nutrition
MUST screening, supplementation, adequate protein intake
SSKIN Bundle — Detailed Implementation
Mild–moderate risk (Braden 13–18). Constant low pressure. Examples: Viscofoam, Tempur. Lower cost, no power required.
High–very high risk (Braden ≤12). Electrically powered cells inflate/deflate alternately to redistribute pressure. Required for ICU, immobile patients. Examples: Nimbus, Alpha Active.
- Select mattress based on Braden/Waterlow score — document rationale
- Check mattress integrity (no bottoming out — hand under mattress test)
- Heel off surface: foam wedges/heel float devices for all patients with Braden ≤14
- Operating theatre table overlay for procedures >2 hours
- Wheelchair/chair cushion for chairfast patients (gel/foam pressure-relieving)
- Full skin assessment minimum every 2 hours (at each repositioning)
- Inspect all bony prominences: sacrum, coccyx, heels, malleoli, ischial tuberosities, trochanters, occiput, elbows, scapulae
- Inspect all medical device contact points every shift (minimum 8-hourly)
- Assess for non-blanchable erythema using blanching test (finger pressure test or glass tumbler)
- In darker skin tones: assess warmth (local heat >1°C), firmness/induration (boggy or firm), and patient-reported pain/discomfort
- Use body map/wound chart for documented findings with date and time
- Photograph any skin changes — time-stamped clinical photography
- Minimum every 2 hours for all at-risk patients
- Every 1 hour for very high risk (Braden ≤9) or if pressure injury present
- Use repositioning chart — document position, time, skin inspection findings, nurse signature
- 30-degree lateral tilt — NOT 90-degree (avoids direct pressure on greater trochanter)
- Avoid placing patient directly on existing pressure injury
- Avoid positioning over medical devices where possible
- Use slide sheets — never drag patient across surface
- Semi-recumbent: head of bed 30° maximum (to reduce shear) unless clinical contraindication
- Heels must be completely offloaded from bed surface — foam heel props or commercial heel float devices
- Do NOT use rings/donuts — they create circular pressure
- Inspect heels every 2 hours — particularly in diabetic, vascular and post-operative patients
- Heel dressings (e.g. Mepilex Border Heel) for very high risk patients as prophylactic dressings
- Moisture-Associated Skin Damage (MASD) — distinct from pressure injury but co-exists and increases risk
- Implement SICP — Structured Skin Integrity Care Plan
- Cleanse skin after each episode of incontinence using pH-balanced skin cleanser (pH 4–5.5)
- Apply barrier cream/film after each cleanse (e.g. Cavilon No-Sting Barrier Film, Sudocrem)
- Avoid soap and water — alkaline pH disrupts skin's acid mantle
- Identify and treat underlying cause of incontinence: UTI, constipation, drug side effects
- Consider continence aids: containment products, catheterisation (if clinically appropriate)
- In GCC context: hot climate increases perspiration — moisture management extends to perspiration and wound exudate
- Perform on admission and weekly thereafter
- Score 0: Low risk — routine care
- Score 1: Medium risk — observe/document 3-day dietary intake
- Score 2+: High risk — refer to dietitian, initiate nutritional support
- Protein: 1.2–1.5 g/kg/day (increased for wound healing)
- Calories: 30–35 kcal/kg/day
- Fluid: 30–35 mL/kg/day
- Vitamin C: collagen synthesis
- Zinc: cell proliferation and immune function
- Arginine: specific wound healing supplements (e.g. Arginaid, Cubitan)
TIME Framework — Wound Assessment
T — Tissue Type
| Black | Necrotic/eschar — devitalised tissue, requires debridement |
| Yellow | Slough — fibrinous material, requires debridement |
| Red | Granulating — healthy healing tissue, protect and maintain |
| Pink | Epithelialising — new skin growth at wound edges |
I — Infection / Inflammation
- Contamination: micro-organisms present, no host response
- Colonisation: organisms present, multiplying, no host response
- Critical Colonisation: delayed healing, increased exudate, wound pain — treat with antimicrobial dressing
- Local Infection: cellulitis, erythema >2cm, warmth, pain, purulent exudate
- Systemic Infection: fever, raised WCC, sepsis — systemic antibiotics, urgent review
M — Moisture Balance
- Assess exudate level: none / low / moderate / high
- Assess exudate type: serous / serosanguineous / haemosanguineous / purulent
- Dry wound bed: needs moisture donation (hydrogel/hydrocolloid)
- Heavily exuding: needs absorption (foam/alginate)
- Macerated periwound skin: barrier film before dressing
E — Edge of Wound
- Advancing edge: healing progressing — continue current treatment
- Non-advancing edge: rolled/raised edges — stalled healing, consider debridement/reassessment
- Undermining: tissue destruction beneath wound edge — probe with cotton-tipped applicator, document with clock positions
- Sinus/tunnelling: document depth and direction
Wound Measurement & Documentation
Measurement Technique
- Length × Width: greatest length (head-to-toe axis) × greatest width (side-to-side)
- Depth: sterile probe to deepest point (cm)
- Undermining: probe inserted along wound edges — document o'clock positions and depth
- Measure at every dressing change — document on wound assessment chart
- Clinical photography: time-stamped, with ruler, patient consent obtained
Wound Swab — Levine Method
- Clean wound first with sterile saline — remove surface debris
- Use moistened sterile swab (normal saline)
- Apply 10-point Levine technique: 1 cm² area, rotating swab with sufficient pressure to express fluid from wound tissue
- Targets deep wound tissue flora rather than surface contaminants
- Label specimen: wound site, date, time, clinical indication
- Send immediately to microbiology
Dressing Selection by Wound Type
| Wound Condition | Goal | Dressing Type | Examples |
|---|---|---|---|
| Necrotic / Eschar | Autolytic debridement | Hydrocolloid / Hydrogel | DuoDERM, Intrasite Gel, Aquaform |
| Sloughy Yellow | Debridement + moisture balance | Hydrocolloid / Hydrofibre / NPWT | DuoDERM Extra Thin, Aquacel Extra |
| Infected / Critical Colonisation | Antimicrobial, biofilm disruption | Silver-containing dressings | Mepilex Ag, Aquacel Ag, Biatain Ag |
| Moderate exudate, granulating | Absorb exudate, protect tissue | Foam dressing | Mepilex Border, Biatain, Allevyn |
| Low exudate, epithelialising | Maintain moist environment | Thin film / thin hydrocolloid | Tegaderm, DuoDERM Thin, Opsite |
| High exudate | High absorption | Alginate / hydrofibre | Kaltostat, Aquacel, Sorbsan |
| Cavity / sinus | Fill dead space, absorb | Ribbon/cavity foam | Aquacel ribbon, Allevyn cavity |
| Prophylactic — high risk site | Prevent pressure injury | Multi-layer soft silicone foam | Mepilex Border Lite, Allevyn Life |
Surgical Debridement & NPWT
Surgical Debridement Indications
- Extensive necrosis — large eschar not responding to autolytic methods
- Infection tracking / spreading cellulitis / sepsis source
- Stage 4 pressure injury with bone/tendon involvement
- Osteomyelitis (bone infection) requiring surgical clearance
- Sharp/surgical debridement by trained clinician (TVN/surgeon/doctor)
- Enzymatic debridement: Collagenase (Santyl) — adjunct option
NPWT — Negative Pressure Wound Therapy
- Continuous or intermittent sub-atmospheric pressure (-80 to -125 mmHg)
- Promotes granulation, reduces oedema, removes exudate
- Indications: large cavity wounds (Stage 3/4), post-surgical wounds, dehisced wounds
- Contraindications: untreated osteomyelitis, malignancy in wound, unexplored fistula, dry necrosis (eschar)
- Change foam every 48–72 hours (or per manufacturer guidance)
- Devices: V.A.C. (KCI), Avelle, PICO (closed incision NPWT)
Documentation Standards
Required Documentation Elements
- Initial skin assessment on admission (date/time/nurse name)
- Risk assessment score (Braden/Waterlow) with total and subscores
- Body map marking of all skin findings
- Wound assessment chart (TIME framework, measurements)
- Time-stamped clinical photography with consent
- Repositioning chart: position, time, skin check, signature
- Dressing change record: wound appearance, dressing used, next change date
- Nutritional screening score and actions taken
- Patient/family education provided — what, when, who
- Tissue viability nurse referral and outcome
Incident Reporting — DATIX / Never Events
- Category 3, 4 and DTPI acquired in hospital are mandatory incident reports
- Report within 24 hours of identification
- Distinguish: ward-acquired vs community-acquired vs unavoidable
- DATIX: detail wound location, stage, date first noted, risk factors, preventive measures in place
- Category 4 and DTPI: trigger formal root cause analysis (RCA)
- RCA examines: assessment adequacy, repositioning compliance, equipment use, documentation, staffing
- Actions shared with ward team as learning outcome
Tissue Viability Nurse (TVN) Referral
Referral Triggers
- Any Category 2 pressure injury not improving within 2 weeks
- Any Category 3 or 4 pressure injury — automatic referral
- Any DTPI (Deep Tissue Pressure Injury)
- Unstageable wound requiring specialist debridement assessment
- Complex wound: fistula, sinus, tunnelling, osteomyelitis suspected
- Patient requiring NPWT initiation or review
- Wound not responding to 2 weeks of standard treatment
Legal & Professional Framework
- Duty of care: nurse has legal obligation to provide competent pressure injury prevention
- Negligence: failure to assess, prevent, treat or document can constitute clinical negligence
- NMC Code (UK) / DHA/SCFHS Standards: registered nurses responsible for maintaining competency in wound care
- Hospital Trust / facility liable for systemic failures: staffing, equipment, education
- Cost per pressure ulcer: £1,214–£14,108 depending on category (NHS data)
Patient & Family Education
In-Hospital Education
- Explain what pressure injuries are and why patient is at risk
- Demonstrate repositioning technique for self-repositioning (if able)
- Teach pressure-relieving positions: 30° tilt, pillow under calves
- Encourage patient/family to report new skin pain, redness, warmth
- Nutritional guidance: high-protein diet, hydration importance
Discharge Planning & Community Referral
- Carer training: repositioning, skin inspection, dressing technique
- Prescribe appropriate pressure-relieving cushion for wheelchair/chair use
- Community wound care referral: district nursing / community TVN
- Provide written wound care plan with dressing type, frequency, review date
- Red flags for GP/ED re-referral: wound deterioration, infection signs, fever
GCC-Specific Context
Accreditation Standards in GCC
- JCI (Joint Commission International): pressure injury prevention in IPSG.6 — international patient safety goals
- CBAHI (Saudi Arabia): NSCP standards include pressure injury rates as quality indicator
- DHA (Dubai Health Authority): tissue viability standards aligned with NICE/NHS frameworks
- DOH (Abu Dhabi): hospital quality standards include wound care competency
- SCFHS (Saudi Commission for Health Specialities): pressure injury content in nursing licensing exams
- Pressure injury rate reported as hospital quality indicator — lower rates linked to accreditation scores
GCC-Specific Clinical Challenges
- High ICU-to-bed ratios in GCC tertiary hospitals — concentrated very high risk population
- Hot climate: increased perspiration → moisture-associated skin damage (MASD) even in non-incontinent patients
- Moisture management extended to sweat and wound exudate in air-conditioned and non-air-conditioned settings
- Diverse patient population: different skin tones require adapted Stage 1 assessment methods
- High rates of diabetes mellitus and obesity in GCC — peripheral neuropathy and vascular risk factors common
- Availability of alternating pressure mattresses varies — document when unavailable and escalate
Darker Skin Tone — Assessment Adaptation
- Palpate for localised warmth — may present as warmer than surrounding tissue
- Palpate for firmness or bogginess (oedema vs induration)
- Ask patient: localised pain, tenderness or burning sensation
- Use subdued lighting at different angles to detect colour change
- Compare symmetrically — assess equivalent area on opposite side
- Purple/maroon hue rather than red — indicates DTPI in darker skin
MASD vs Pressure Injury — Differential
| Feature | MASD | Pressure Injury |
|---|---|---|
| Cause | Moisture/chemical | Pressure/shear |
| Location | Skin folds, perineum | Bony prominences |
| Shape | Irregular/diffuse | Regular, defined |
| Depth | Superficial | Can be deep |
| Edges | Irregular, 'kissing' lesions | Regular/distinct |
SCFHS / DHA / DOH Exam Preparation
Braden Scale — Key Exam Points
- Total range: 6–23
- 6 domains (not 5, not 7)
- Friction & Shear scored 1–3 only
- Very high risk: ≤9
- No risk: ≥19
- Lower = higher risk
NPIAP Staging — Key Exam Points
- Stage 1: intact skin, non-blanchable
- Stage 2: partial thickness, blister OK
- Stage 3: fat visible, NOT bone
- Stage 4: bone/tendon/muscle visible
- Unstageable: eschar/slough obscures — cannot be staged
- DTPI: deep purple/maroon, intact OR broken skin
SSKIN — Key Exam Points
- S = Surface (mattress)
- S = Skin inspection
- K = Keep moving (repositioning)
- I = Incontinence management
- N = Nutrition
- 2-hourly minimum repositioning
- 30° lateral tilt (not 90°)
Dressing Selection — Exam Points
- Silver = infection/critical colonisation
- Foam = moderate exudate
- Hydrocolloid/hydrogel = dry/necrotic
- Alginate = high exudate
- Thin film = epithelialising/low exudate
- NPWT = cavity/Stage 3–4
Legal — Exam Points
- Cat 3/4/DTPI = mandatory incident report
- Cat 4/DTPI = Root Cause Analysis
- TVN referral: Cat 2 not improving / any Cat 3+
- Cost: £1,214–£14,108 per ulcer
- Never Event = avoidable Cat 3/4 hospital-acquired
TIME Framework — Exam Points
- T = Tissue (necrotic/slough/granulating/epithelialising)
- I = Infection/inflammation
- M = Moisture balance
- E = Edge of wound
- Levine method = wound swab technique