Updated Apr 2026 ← Back to Index
PICU Fundamentals
Critical Reminder: Normal paediatric values differ markedly by age. Always interpret vitals in context — a HR of 150 is normal in a neonate but tachycardic in an adolescent.

📊 Age-Based Normal Vital Signs

Age GroupHR (bpm)RR (breaths/min)Systolic BP (mmHg)SaO₂ (%)
Neonate (0–1 mo)100–16040–6060–90≥95
Infant (1–12 mo)100–16030–6070–100≥95
Toddler (1–3 yr)90–15024–4080–110≥95
Preschool (3–5 yr)80–14022–3480–110≥95
School (6–12 yr)70–12018–3085–120≥95
Adolescent (>12 yr)60–10012–2090–130≥95
Hypotension threshold: Systolic BP < 70 + (2 × age in years) for children 1–10 yr. Below this = hypotensive shock.

🚨 PEWS — Paediatric Early Warning Score

Scores 0–3 in each domain. Total ≥4 = escalate; ≥6 = consider PICU referral immediately.

Domain0123
BehaviourPlaying/AppropriateSleepingIrritableLethargic/Confused
CardiovascularPink, CRT <2sPale, CRT 3sGrey, CRT 4sGrey/mottled, CRT ≥5s
RespiratoryNormal rate, no recessionRR+10, mild recessionRR+20, moderate recession5+ below normal or sternal recession
Nebuliser/O₂None4+ L/min O₂≥50% O₂ or hourly neb
Vomiting post-opNone≥3× / bilious

📈 PRISM-III Score Overview

Paediatric Risk of Mortality III — calculated in first 12 hours of PICU admission. Predicts risk of death.

Variables Assessed (17 total)

  • Systolic BP (age-specific ranges)
  • Temperature (>40°C or <33°C = high risk)
  • Mental status (GCS adaptation)
  • Heart rate (age-specific)
  • Pupillary reflexes (abnormal = 4–7 pts)
  • PT, PTT, total bilirubin
  • Potassium, calcium, glucose, bicarbonate
  • PCO₂, PaO₂/FiO₂ ratio
  • Creatinine (age-adjusted)
Score >20 = mortality risk significantly elevated. Used for benchmarking and ICU audit, not bedside treatment decisions alone.

👨‍👩‍👧 Family-Centred Care Principles in PICU

Dignity & Respect

  • Listen to family knowledge of the child
  • Honour cultural and religious values
  • Avoid terminology that diminishes family role
  • Individualise care to family preferences

Information Sharing

  • Daily family briefings from senior nurse or physician
  • Use interpreters when Arabic/English barrier exists
  • Written summaries of plan of care
  • Honest, timely communication at all stages

Participation

  • Invite family in ward rounds where appropriate
  • Encourage comfort touch, reading to child
  • Teach suctioning/NG care to willing parents
  • Family presence during procedures — supported
Paediatric Airway & Ventilation
WETFLAG: Memorise this mnemonic — it provides immediate weight-based dosing for all paediatric emergencies. Use the calculator tab for instant results.

🔤 WETFLAG — Emergency Drug Dosing Mnemonic

LetterParameterFormulaNotes
WWeight (kg)(Age + 4) × 2 for 1–10 yrOr use Broselow tape; neonates use actual weight
EEnergy (Joules)4 J/kgBiphasic defibrillation; max 200 J
TTube (ETT size, mm)(Age/4) + 4 uncuffed; (Age/4) + 3.5 cuffedHave size above and below available
FFluid (mL)20 mL/kg bolus (sepsis); 10 mL/kg in shock with cardiac riskReassess after each bolus
LLorazepam (mg)0.1 mg/kg IVMax 4 mg; for seizures
AAdrenaline (mL of 1:10,000)0.1 mL/kg IV/IO= 0.01 mg/kg; repeat every 3–5 min in arrest
GGlucose (mL of 10%)2 mL/kg of 10% glucoseFor hypoglycaemia; recheck BG 15 min after

🫁 Cuffed vs Uncuffed ETT Selection

Uncuffed ETT (traditional guidance)

  • Preferred in children <8 years (narrow cricoid = natural seal)
  • Less risk of subglottic mucosal injury
  • Leak pressure should be 20–25 cmH₂O (if using uncuffed)

Cuffed ETT (current evidence-based)

  • Now safe and preferred in PICU even for infants
  • Allows better ventilation control, reduced contamination
  • Cuff pressure: maintain 20–25 cmH₂O (use manometer)
  • Formula: size = (Age/4) + 3.5; or 0.5 less than uncuffed
Lip-to-tip (ETT depth): 3 × ETT internal diameter (cm), or (Age/2) + 12 cm for oral ETT in children.

⚙️ Paediatric Ventilation Settings

Standard Initial Settings

ParameterTarget
Tidal Volume (Vt)6–8 mL/kg IBW (lung protective)
PEEP5–8 cmH₂O (start 5; increase for hypoxia)
FiO₂Titrate to SaO₂ 94–98%
RateAge-appropriate (≈ normal RR)
Peak Pressure<30 cmH₂O (avoid barotrauma)
I:E Ratio1:2 standard; 1:3–4 in obstruction (asthma)
Target PaCO₂35–45 mmHg (allow permissive hypercapnia in ARDS)

🌀 High-Frequency Oscillatory Ventilation (HFO)

Indications

  • Severe ARDS refractory to conventional ventilation
  • Oxygenation Index (OI) >20–40
  • Air leak syndromes (PIE, pneumothorax)
  • Persistent pulmonary hypertension of newborn (PPHN)

Key Parameters

  • MAP: Start 2–3 cmH₂O above conventional MAP
  • Frequency: 8–15 Hz (lower = more CO₂ clearance)
  • Amplitude (ΔP): Titrate to chest "wiggle" to umbilicus
  • FiO₂: Wean as oxygenation improves
OI Formula: OI = (MAP × FiO₂ × 100) ÷ PaO₂. OI >40 = consider ECMO consultation.

💨 High-Flow Nasal Cannula (HFNC) in Children

Indications

  • Bronchiolitis (first-line after standard O₂ fails)
  • Mild-moderate respiratory failure
  • Post-extubation support
  • Severe pneumonia — bridge to intubation decision

Flow Rates

AgeStarting FlowMax Flow
Neonate2–4 L/min6 L/min
Infant4–8 L/min2 L/kg/min
Child1 L/kg/min40–50 L/min
Failure criteria: Persisting RR >70% above normal, SpO₂ <92% on FiO₂ 0.6, increasing work of breathing, exhaustion — escalate immediately.
PICU Drug Dosing

💉 Vasoactive Infusions

DrugDose RangeNotes
Dopamine5–20 mcg/kg/min5–10: inotropic; >10: vasopressor
Dobutamine5–20 mcg/kg/minInotropic; no significant vasopressor effect
Noradrenaline0.05–2 mcg/kg/minStart 0.05–0.1; vasopressor of choice in warm shock
Adrenaline0.05–1 mcg/kg/minCold shock / cardiac arrest; high doses → tachycardia
Milrinone0.25–0.75 mcg/kg/minPost-cardiac surgery; PDE-3 inhibitor; no loading in PICU
Vasopressin0.0003–0.002 units/kg/minRefractory septic shock; catecholamine-sparing

💊 Sedation & Analgesia

DrugBolusInfusion
Midazolam0.05–0.1 mg/kg IV0.02–0.1 mg/kg/hr (max 0.4)
Morphine0.05–0.1 mg/kg IV10–40 mcg/kg/hr
Fentanyl1–2 mcg/kg IV1–4 mcg/kg/hr
DexmedetomidineAvoid loading in PICU0.2–1.4 mcg/kg/hr (titrate)
Ketamine1–2 mg/kg IV (procedural)0.1–0.5 mg/kg/hr (analgesia)
Propofol1–2 mg/kg IV (induction)Avoid infusion >4 hrs in children (PRIS risk)
Chloral hydrate25–50 mg/kg PO/PRProcedural sedation; max 100 mg/kg

🧠 Paralytic Agents (Neuromuscular Blockade)

DrugTypeDoseDuration
SuxamethoniumDepolarising1–2 mg/kg IV (infant: 2 mg/kg)5–10 min
RocuroniumNon-depol0.6–1.2 mg/kg IV30–60 min
VecuroniumNon-depol0.1 mg/kg IV bolus25–40 min
Vecuronium infusionNon-depol0.05–0.1 mg/kg/hrContinuous
AtracuriumNon-depol0.5 mg/kg IV; 5–10 mcg/kg/min20–35 min
SugammadexReversal2–4 mg/kg IV (routine reversal)Immediate
Caution: Suxamethonium contraindicated in burns, crush injury, hyperkalaemia, myopathies, and malignant hyperthermia risk.

⚡ Emergency Drugs

DrugDoseIndication
Adrenaline 1:10,0000.1 mL/kg IV/IOCardiac arrest; anaphylaxis 0.01 mg/kg IM
Atropine0.02 mg/kg IV (min 0.1 mg)Bradycardia; pre-intubation in infants
Adenosine0.1 mg/kg rapid IV (max 6 mg first dose)SVT; escalate to 0.2 then 0.3 mg/kg
Amiodarone5 mg/kg IV over 20 min (VT/VF: 5 mg/kg rapid)Pulseless VT/VF, SVT
Sodium bicarbonate1 mmol/kg slow IV (8.4% = 1 mL/kg; dilute 1:1)Severe metabolic acidosis, hyperkalaemia
Calcium gluconate 10%0.5–1 mL/kg IV slowlyHypocalcaemia, hyperkalaemia, CCB toxicity
Naloxone0.01 mg/kg IV (titrate to effect)Opioid reversal
Flumazenil0.01 mg/kg IV (max 0.2 mg)Benzo reversal — use cautiously

🧬 Anticonvulsant Ladder

StepDrugDoseRouteTiming
1stDiazepam0.2–0.5 mg/kg (max 10 mg)IV / PR0–5 min; may repeat once
1stLorazepam0.1 mg/kg IV (max 4 mg)IV / INPreferred if IV access
1stMidazolam0.2 mg/kg buccal; 0.1 mg/kg IVBuccal / IV / IMPrehospital first-line
2ndLevetiracetam40–60 mg/kg IV (max 3 g)IV over 5–15 min5–20 min post-benzo
2ndPhenytoin / Fosphenytoin20 mg/kg IV (max 1 g)IV over 20 min (monitor ECG)Alternative 2nd line
2ndPhenobarbitone20 mg/kg IV (max 1 g)IV over 20–30 minNeonates — 1st choice 2nd agent
3rdThiopental sodium2–5 mg/kg IV; infusion 1–5 mg/kg/hrIV — needs intubationRefractory status
3rdMidazolam infusion0.05–0.4 mg/kg/hrIV continuousRefractory status
Common PICU Conditions

🦠 Paediatric Septic Shock (PALS Algorithm)

Recognition (within 1 hour)

  • Fever/hypothermia + altered mental status
  • Warm shock: flash CRT, bounding pulse, wide pulse pressure
  • Cold shock: prolonged CRT (>3s), weak pulse, mottled
  • Lactate >2 mmol/L or >4 mmol/L = severe

Management Bundle

  • Fluid: 10–20 mL/kg isotonic boluses; reassess after each. Caution if signs of fluid overload (rales, hepatomegaly). Up to 40–60 mL/kg in 1st hour without cardiac disease
  • Antibiotics: Within 1 hour of recognition — broad spectrum empirical
  • Vasopressor: Cold shock → Adrenaline (start 0.05 mcg/kg/min); Warm shock → Noradrenaline (start 0.05 mcg/kg/min)
  • Corticosteroids: Hydrocortisone 1–2 mg/kg Q6H if catecholamine-resistant shock
  • Target: MAP ≥ (age × 1.5 + 40); ScvO₂ ≥70%; lactate normalisation
GCC Note: High prevalence of gram-negative sepsis (Klebsiella, Pseudomonas) in NICU graduates. Consider antifungals (fluconazole/caspofungin) in immunocompromised.

⚡ Status Epilepticus

  • Definition: seizure >5 minutes or recurrent without recovery
  • Refractory: persisting >30 min despite 2 agents

Immediate Actions

  • Airway, O₂ — suction, nasal airway if needed
  • BGL — if low give 10% glucose 2 mL/kg
  • ECG, temperature, Na, Ca, Mg levels
  • EEG monitoring once stabilised

Follow anticonvulsant ladder (see Drug tab)

EEG Monitoring Targets

  • Burst suppression ratio 50–90% in refractory SE
  • Continuous cEEG if paralysed (detect subclinical seizures)
  • Wean sedation/AEDs gradually when seizure-free 24–48 hrs
GCC Context: Metabolic causes (organic acidaemias, urea cycle disorders) more prevalent due to high consanguinity — check amino acids, ammonia early in neonates/infants.

🍬 Paediatric DKA Management

Criteria

  • BGL >11 mmol/L + ketones >3 mmol/L or ketonuria
  • pH <7.3 or bicarbonate <15 mmol/L
  • Severity: Mild (pH 7.2–7.3), Moderate (7.1–7.2), Severe (<7.1)

Fluid Management (ISPAD 2022)

  • Restoration only if shocked: 10 mL/kg 0.9% NaCl over 30 min
  • Replace deficit + maintenance over 48 hours using 0.9% NaCl
  • Add 40 mmol/L KCl once urine output confirmed
  • Switch to 0.45% NaCl + glucose 5% when BGL <14 mmol/L

Insulin

  • Start 0.05–0.1 units/kg/hr after 1–2 hrs of fluid
  • No insulin bolus in children
  • Target BGL reduction: 2–5 mmol/L/hr
DO NOT give bicarbonate in paediatric DKA — increases risk of cerebral oedema. Only consider if pH <6.9 with haemodynamic compromise under senior supervision.
Cerebral oedema: Headache, bradycardia, Cushing's triad, pupil change → mannitol 0.5–1 g/kg immediately; consider hypertonic saline 3% 3–5 mL/kg.

🫁 Bronchiolitis (RSV)

Diagnosis

  • Age <12 months, first episode wheeze
  • RSV most common (Oct–Mar in GCC); also Rhinovirus, hMPV
  • Signs: tachypnoea, subcostal/intercostal recession, fine crackles, wheeze

Supportive Care (EVIDENCE-BASED)

  • Nasal suctioning — frequent, especially before feeds
  • O₂ to maintain SpO₂ ≥90–92%
  • NG feeds if >30–40% increased work of breathing
  • HFNC: first escalation for moderate-severe (2 L/kg/min)
  • CPAP/BiPAP: if HFNC fails or severe apnoea
  • Intubation: respiratory failure, recurrent apnoea
NOT recommended: Salbutamol, adrenaline nebulisers, steroids, antibiotics, ribavirin — not routinely evidence-based in bronchiolitis.

🧠 Bacterial Meningitis

Empirical Antibiotics (age-based)

AgeAntibioticDose
<3 monthsAmpicillin + Cefotaxime200 mg/kg/day ÷ 6H
3 mo – 18 yrCeftriaxone100 mg/kg/day ÷ 12H (max 4g/day)
Any age (MRSA risk)+ Vancomycin15 mg/kg Q6H

Dexamethasone

  • 0.15 mg/kg Q6H × 4 days
  • Give 10–20 min BEFORE or with first antibiotic dose
  • Greatest benefit: H. influenzae and pneumococcal meningitis
  • Reduces hearing loss; less clear benefit for other organisms

LP Timing — Contraindications to Immediate LP

  • GCS <9 or deteriorating conscious level
  • Papilloedema / focal neurological signs
  • Haemodynamic instability
  • Coagulopathy (platelets <50, INR >1.5)
  • Skin infection over LP site
Important: Start antibiotics immediately — do NOT delay for CT or LP if contraindications present. LP can be performed after 48 hours if clinically stable.

CSF Interpretation

WCCProteinGlucose
Bacterial>1000 PMN↑↑↓ (<50% serum)
Viral10–500 lymphNormal/↑Normal
TB100–500 lymph↑↑↑↓↓
PICU Procedures & Monitoring

🦴 Intraosseous (IO) Access — EZ-IO

Sites (preferred order)

  • Proximal tibia: 2 cm below tibial tuberosity, medial flat surface (most common in children)
  • Distal tibia: Proximal to medial malleolus (alternative)
  • Proximal humerus: Greater tubercle — preferred in adults; used in older children
  • Distal femur: Neonates/infants if tibia inaccessible

Needle Sizes (EZ-IO)

  • Pink (15 mm): 3–39 kg
  • Blue (25 mm): ≥40 kg or obese smaller patient
  • Yellow (45 mm): excessive tissue depth

Contraindications

  • Fracture ipsilateral to insertion site
  • Previous IO in same bone within 24 hrs
  • Overlying infection or burn
  • Osteogenesis imperfecta
  • Prosthetic limb
All IV drugs/fluids/blood products can be given IO. Flush each drug with 5–10 mL NS. Use pressure bag or rapid infuser for fluids.

🩸 Arterial Line in Small Patients

Sites

  • Radial artery: First choice; Allen's test first (or pulse ox on thumb)
  • Femoral artery: Emergency, large vessel; monitor for ischaemia
  • Dorsalis pedis / posterior tibial: Alternative in infants
  • Umbilical artery: Neonates only; UAC

Catheter Size

  • Neonates: 24G
  • Infants/toddlers: 22G
  • Children: 20–22G

Maintenance

  • Heparinised flush (1–2 units/mL NS), continuous at 1–3 mL/hr
  • Zero transducer at mid-axillary line (4th ICS)
  • Check limb perfusion hourly — colour, CRT, temperature
  • Site change every 5–7 days or at first sign of concern

💙 PICC Line Care

Insertion Considerations

  • Confirm tip position at cavoatrial junction on X-ray
  • Measure arm circumference before insertion (oedema monitoring)
  • Single-lumen preferred in children unless dual access critical

Daily Care Bundle (CLABSI prevention)

  • Hand hygiene (5 moments)
  • Assess line necessity every shift — remove if not needed
  • CHG 2% dressing change every 7 days (or if wet/soiled)
  • Scrub the hub × 15 sec before each access
  • Closed needleless system; blood cultures before starting antibiotics
  • Maintain dressing integrity; document in care plan
CLABSI bundle compliance reduces infection rates by 65–70% in PICU. Document all bundles on daily safety checklist.

📊 Pain & Sedation Assessment

FLACC Scale (0–10) — Non-Verbal / Intubated

Domain012
FaceNo expressionOccasional grimaceFrequent frown/clenched jaw
LegsNormal/relaxedUneasy/restlessKicking/drawn up
ActivityLying quietlySquirming/tenseArched/rigid/jerking
CryNo cryMoans/whimpersCrying steadily
ConsolabilityContent/relaxedReassurableInconsolable

COMFORT-B Sedation Scale

Scores 6 domains (alertness, calmness, respiratory, crying, movement, muscle tone). Score 6–10 = over-sedated; 11–22 = optimal; 23–30 = under-sedated. Reassess Q4H.

NRS Scale

Numeric Rating Scale (0–10) for children ≥6 years who can self-report. Use Wong-Baker FACES for age 3–6.

🧠 Continuous EEG (cEEG) Monitoring in PICU

Indications

  • Refractory status epilepticus
  • Post-cardiac arrest (therapeutic hypothermia)
  • Hypoxic-ischaemic encephalopathy (HIE)
  • Encephalitis / meningitis with altered consciousness
  • Post-neurosurgery with seizure risk
  • Unexplained altered consciousness
  • Metabolic encephalopathy (hyperammonaemia)

Nursing Responsibilities

  • Apply electrodes according to 10-20 system (or 10-10 in neonates)
  • Document clinical events with EEG annotations
  • Minimise movement artefact — note suction, procedures
  • Notify neurologist of electrographic seizures
  • Monitor electrode integrity every 4 hours
  • Integrate EEG findings with clinical status in handover
GCC Context

🏥 Major Paediatric Hospitals in GCC

HospitalLocationNotes
Batterjee Children's Hospital (BCH)Riyadh, KSATertiary paediatric centre; large PICU; cardiac surgery
National Guard Health Affairs – PaedsRiyadh, KSAIntegrated paediatric services; PICU & NICU
Sheikh Khalifa Medical City (SKMC)Abu Dhabi, UAETertiary PICU; ECMO program; cardiac PICU
Al Jalila Children's Specialty HospitalDubai, UAEDubai's first dedicated children's hospital; Level III PICU
Al Wasl Hospital – PaediatricsDubai, UAEGeneral paediatrics; lower-acuity admissions; step-down
Hamad Medical Corp – Women's & NeonatalDoha, QatarLargest NICU in Qatar; paediatric emergency
Salmaniya Medical ComplexManama, BahrainNational referral centre for paediatrics
Khoula HospitalMuscat, OmanTertiary surgical centre; paediatric trauma PICU

🧬 Genetic Conditions Prevalent in GCC

Consanguinity rates 20–60% in GCC → markedly elevated autosomal recessive disease prevalence

Inborn Errors of Metabolism (IEM)

  • Phenylketonuria (PKU) — screened neonatally in all GCC states
  • Maple Syrup Urine Disease (MSUD) — encephalopathy, sweet urine odour
  • Urea Cycle Disorders (OTC deficiency) — hyperammonaemia, coma
  • Organic Acidaemias (MMA, PA, IVA) — metabolic acidosis, ketonuria
  • Fatty Acid Oxidation Disorders (MCAD) — hypoketotic hypoglycaemia
  • Glycogen Storage Diseases — hepatomegaly, hypoglycaemia

Congenital Heart Disease

  • Higher prevalence than global average in Arabian Peninsula
  • VSD, ToF, TGA, HLHS common in PICU referrals
  • Post-cardiac surgery patients: monitor SVC, PA pressures; pulmonary hypertensive crisis risk

Haematological

  • Sickle Cell Disease — SCA crisis, acute chest syndrome, stroke
  • Beta-Thalassaemia major — chronic transfusion, iron overload
  • G6PD deficiency — haemolysis with oxidant exposure

👩‍⚕️ PICU Staffing Ratios — GCC Standards

CountryNurse:Patient RatioPhysician Cover
Saudi Arabia (MOH)1:1 (ventilated); 1:2 (stable)Resident 24/7; Intensivist consultant cover
UAE (DOH/DHA)1:1–2 per acuityFellow 24/7; Attending consultant on-call
Qatar (HMC)1:1 (ventilated)Board-certified intensivist 24/7 in-house
Kuwait (MOH)1:2 standardSenior resident + consultant cover
Bahrain1:2 (varies)Consultant on-call 24/7
Oman1:1–2Resident in-house; consultant reachable
GCC Trend: All major PICU centres moving toward 24/7 in-house attending intensivist model aligned with SCCM/ESICM standards.

🚁 PICU Transport to Tertiary Centre

Stabilise Before Transport ("STABLE" Mnemonic)

  • S — Sugar (BGL 4–8 mmol/L)
  • T — Temperature (36.5–37.5°C)
  • A — Airway (secure ETT; confirm position; CXR)
  • B — Blood pressure (stable; vasopressors drawn up)
  • L — Lab work (sent and reviewed)
  • E — Emotional support (family briefed; consent taken)

Transport Team Minimum

  • Paediatric transport nurse (PICU-trained)
  • Physician (paediatric registrar minimum)
  • Transport equipment: portable ventilator, defibrillator, infusion pumps, drug kit
  • Pre-alert receiving PICU ≥30 min before arrival

🕌 Family Visiting in PICU — Cultural Expectations (GCC)

Visiting Practices

  • Extended family involvement is normative — expect multiple family members
  • Family spokesperson (usually father/elder male) for major decisions
  • Mothers often wish to stay 24/7 — accommodate where safe
  • Prayer times (5×/day) — schedule procedures around if possible
  • Quran recitation at bedside — welcome and normalise

Communication Considerations

  • Use certified medical interpreters for Arabic-speaking families
  • Avoid delivering bad news in busy corridors
  • Privacy for family discussions — dedicated family room
  • Allow family to seek second opinions — facilitate this
  • Discuss prognosis sensitively; avoid blunt prognostic statements

End-of-Life Care

  • Withdrawal of care: sensitive; involves religious guidance (imam)
  • Brain death: must be certified by two senior physicians; family may request time
  • Post-mortem: often declined for religious reasons; respect this
  • Ensure same-gender nurse where possible for personal care
  • Facilitate family time and privacy at end of life
Interactive Calculators

WETFLAG Emergency Calculator

Enter patient weight to auto-calculate all WETFLAG parameters. If weight unknown, estimate using (Age+4)×2 for 1–10 years.

W — Weight
kg (confirmed)
E — Energy
Joules (4 J/kg; max 200 J)
T — Tube (uncuffed)
mm ID
T — Tube (cuffed)
mm ID
F — Fluid Bolus
mL (20 mL/kg)
L — Lorazepam
mg IV (0.1 mg/kg; max 4 mg)
A — Adrenaline 1:10,000
mL IV (0.1 mL/kg)
G — Glucose 10%
mL (2 mL/kg)

Paediatric Drug Dose Calculator

Select a drug and enter weight to calculate recommended dose, max dose, and administration notes.

Drug Name

Patient Weight
Calculated Dose
Maximum Dose
Route
Administration Notes
Disclaimer: Always verify doses against your institution's formulary and with a pharmacist. This calculator is a reference aid only.
MCQ Practice — PICU Nursing (10 Questions)
1. A 2-year-old child weighs 12 kg. Using the WETFLAG mnemonic, what is the correct energy dose for defibrillation?
Energy dose = 4 J/kg. For 12 kg: 4 × 12 = 48 J. Maximum dose is 200 J regardless of weight.
2. Which paediatric pain scale is most appropriate for a 4-year-old intubated child who cannot self-report pain?
FLACC (Face, Legs, Activity, Cry, Consolability) is validated for non-verbal/intubated children. Wong-Baker FACES requires self-report (age 3–6 who can communicate). NRS and VAS require verbal self-report.
3. A 5-year-old child in septic shock presents with warm extremities, flash capillary refill, and bounding pulses. Which vasopressor is the preferred first-line agent?
Warm shock (vasodilatory) is characterised by low SVR. Noradrenaline (norepinephrine) is the preferred vasopressor for warm/distributive shock. Adrenaline is preferred for cold shock (low cardiac output). Dopamine is less favoured due to side effects.
4. You are caring for a 3-year-old with DKA (pH 7.15). The family is concerned and asking about giving bicarbonate. What is the correct response?
ISPAD guidelines clearly state bicarbonate should NOT be given in paediatric DKA as it increases the risk of paradoxical CSF acidosis and cerebral oedema. Insulin and fluid therapy will correct the acidosis. Exception under senior supervision: pH <6.9 with haemodynamic compromise only.
5. When performing intraosseous access with EZ-IO in a 10 kg infant, which needle size should you select?
The Pink 15mm EZ-IO needle is designed for patients 3–39 kg. The Blue 25mm is for ≥40 kg or obese smaller patients. Yellow 45mm is for excessive soft tissue depth. At 10 kg, the Pink needle is correct.
6. A 6-month-old with bronchiolitis has a SpO₂ of 88% despite standard O₂ via nasal cannula at 2 L/min. What is the appropriate next escalation step?
HFNC is the recommended first escalation in bronchiolitis when standard O₂ fails (SpO₂ <90–92%). Salbutamol and steroids are NOT recommended in bronchiolitis (no evidence). Intubation is reserved for respiratory failure or recurrent apnoea — not as the next step here.
7. What is the correct first-line dose of adenosine for SVT in a 20 kg child?
Adenosine first dose = 0.1 mg/kg (max 6 mg), rapid IV push followed immediately by flush. For 20 kg: 0.1 × 20 = 2 mg. Second dose: 0.2 mg/kg (max 12 mg). Must be given as rapid bolus close to heart (antecubital or central).
8. In the GCC context, which of the following explains the higher prevalence of inborn errors of metabolism compared to global averages?
Consanguinity (marriage between relatives) rates in GCC countries range from 20–60%, significantly increasing the chance of autosomal recessive conditions including inborn errors of metabolism (PKU, MSUD, organic acidaemias), haemoglobinopathies, and congenital heart disease. All GCC states have expanded neonatal screening programs.
9. A PEWS score of 6 is calculated for a ward patient. What is the appropriate action?
PEWS ≥4 requires escalation; PEWS ≥6 mandates urgent medical review and consideration of PICU referral immediately. PEWS is designed as an early warning — the purpose is to act before full deterioration. Never delay escalation while administering treatments alone.
10. What is the maximum cuff pressure that should be maintained for a cuffed ETT in a PICU patient?
ETT cuff pressure should be maintained at 20–25 cmH₂O using a manometer. Pressures below 20 cmH₂O risk aspiration and inadequate seal. Pressures above 25–30 cmH₂O compromise tracheal mucosal blood flow and risk tracheal stenosis. Check Q4–8H and document.