GCC Context: Asthma prevalence in children across the UAE and Saudi Arabia reaches 20–30%, among the highest globally. Desert dust storms (shamal), indoor allergens in high-density housing, and shisha smoke exposure are key regional drivers.
Asthma diagnosis in children under 5 is predominantly clinical — spirometry is unreliable in this age group. Pattern recognition of symptoms is essential.
Symptoms variable in frequency, often triggered by URTI. Response to bronchodilators (salbutamol trial) supports but does not confirm diagnosis.
The API identifies children under 3 with recurrent wheeze likely to develop persistent asthma.
Positive API (1 major + 2 minor, or ≥3 episodes/year): 77% chance of active asthma at school age. Supports early treatment.
| Condition | Peak Age | Key Features | Distinguishing Points |
|---|---|---|---|
| Bronchiolitis | <1 year (peak 2–6 months) | Wheeze, crackles, tachypnoea, subcostal recession, feeding difficulty | RSV in winter; no response to salbutamol; first episode only |
| Viral-Induced Wheeze | 1–5 years | Wheeze only with URTI; no symptoms between episodes | No atopy, no personal/family history; resolves age 5–6 |
| Asthma | Any age (often >3 years) | Episodic wheeze + cough + breathlessness; nocturnal symptoms; exercise-triggered | Atopy present; responds to bronchodilators; symptom-free intervals |
| Other (GERD, foreign body, CF, ring vascular) | Variable | Persistent stridor, failure to thrive, focal signs | No seasonal pattern; poor response to asthma Rx; investigate further |
| Age Group | Recommended Device | Interface | Notes |
|---|---|---|---|
| <2 years | pMDI + spacer | Face mask (tightly fitting) | Parent/carer holds device; tidal breathing technique; 5 breaths per actuation |
| 2–4 years | pMDI + spacer | Mouthpiece (when good seal achieved) | Transition from mask when child can maintain lip seal; still tidal breathing |
| 5+ years | pMDI + spacer or DPI | Mouthpiece | DPI requires sufficient inspiratory flow (≥30 L/min); teach and assess technique |
| Acute attack (any age) | Nebuliser | Face mask or mouthpiece | Salbutamol 2.5mg (<5yr) or 5mg (≥5yr); also use if unable to coordinate spacer |
Evidence: pMDI + spacer delivers equivalent bronchodilation to nebulisation in mild–moderate acute attacks. Preferred in ED and ward — fewer side-effects (tremor, tachycardia).
Effective inhaler education follows a demonstrate–observe–correct model:
Include school nurses, teachers, and child's key contacts. Inhaler technique is a shared responsibility across the child's environment.
| Parameter | Mild | Moderate | Severe | Life-Threatening |
|---|---|---|---|---|
| SpO₂ | ≥95% | 92–95% | <92% | <92% (not responding) |
| PEFR (% predicted) | >50% | 33–50% | <33% | <33% or unmeasurable |
| Speech | Full sentences | Short sentences | Words only | Cannot speak |
| Work of Breathing | None / minimal | Mild recession | Marked recession, accessory muscles | Poor respiratory effort / exhaustion |
| Other Features | — | Tachycardia, tachypnoea | Too breathless to feed/walk | Silent chest, cyanosis, altered consciousness, exhaustion |
Silent chest in a child with asthma = medical emergency. Absent wheeze does not mean improvement — it indicates near-total airway obstruction. Escalate immediately.
Repeat every 20–30 min as needed for first hour
One puff at a time, every 20–30 min x3, then reassess
Every 20–30 min x3, then every 1–4 hr. Driven by O₂ at 6–8 L/min
Nebulised, every 20 min x3 doses, then as required. Add to salbutamol nebule.
For 3–5 days. Start early — reduces hospital admission risk.
Single dose. For life-threatening asthma not responding to initial bronchodilators and steroids.
Helium-oxygen mixture (Heliox 80:20 or 70:30) reduces turbulent airflow. Consider in severe wheeze not responding to bronchodilators. Reduces work of breathing while pharmacological treatment takes effect. Not widely available — specialist/PICU setting only.
Heliox cannot be used if child requires >40% oxygen — helium concentration too low to be effective.
Every child with asthma should have a written, colour-coded PAAP completed jointly with the family, reviewed at least annually and after every acute attack.
| Step | Treatment | Notes |
|---|---|---|
| Step 1 | SABA (salbutamol) PRN only | For intermittent/mild symptoms. Frequent SABA use signals inadequate control — step up. |
| Step 2 | Add low-dose ICS (Fluticasone or Beclomethasone) — age-appropriate device | Start ICS when using SABA >3×/week. Fluticasone 50mcg BD or Beclomethasone 100mcg BD. |
| Step 3 | <5yr: Add LTRA (Montelukast) | ≥5yr: Add LABA (Salmeterol) or LTRA | Montelukast is oral — better adherence in young children. LABA only as add-on to ICS (never alone). |
| Step 4 | Increase ICS dose + LABA. Consider LTRA, Theophylline (older children) | Refer to paediatric respiratory specialist. Confirm diagnosis before escalating. |
| Step 5 | Paediatric respiratory specialist. Consider biologics (severe eosinophilic), oral steroids | Anti-IL5 (mepolizumab) licensed ≥6yr in severe eosinophilic asthma. Multidisciplinary review. |
Step down every 3 months once good control is achieved for 3 months. Always confirm inhaler technique and adherence before stepping up therapy.
A separate school asthma plan should be completed for every school-age child. In GCC, school health nurses are present in most government schools and act as key coordinators.
Call 999 / Go to ED immediately if:
While waiting for emergency services: give up to 10 puffs salbutamol via spacer (1 puff, 5 breaths × 10). Sit child upright. Stay calm.
Pre-treatment with 2 puffs salbutamol 15 minutes before exercise effectively prevents exercise-induced bronchospasm. This does not mean avoiding sport — children should be encouraged to exercise and participate fully.
Many Muslim families in the GCC worry that using an inhaler during Ramadan fasting hours will break the fast. This is a significant barrier to adherence and leads to poorly controlled asthma during Ramadan.
Islamic scholarly consensus (fatwa): Using an inhaler during Ramadan does NOT break the fast. The medication enters the lungs, not the stomach, and there is no nutritional intake.
Advise families to clarify this with their own religious scholar if uncertain — healthcare professionals should not provide religious rulings, but can share that this is the widely accepted medical-religious position.
GCC Exam Boards: DHA (Dubai), DOH (Abu Dhabi), SCFHS (Saudi), QCHP (Qatar). Paediatric asthma is a high-yield topic. Focus on severity classification, correct dosing, inhaler device selection, and PAAP principles.
| Feature | Mild | Moderate | Severe | Life-Threatening |
|---|---|---|---|---|
| SpO₂ | ≥95% | 92–94% | <92% | <92% (not improving) |
| PEFR | >50% | 33–50% | <33% | <33% or unmeasurable |
| Speech | Full sentences | Short sentences | Words only | Cannot speak |
| Salbutamol dose (pMDI) | 2–4 puffs | 4–10 puffs | 4–10 puffs + nebulise | Continuous nebulisation |
| Ipratropium | No | No | Yes | Yes |
| Prednisolone | Consider if no improvement | Yes — start early | Yes — start immediately | IV hydrocortisone |
| Magnesium IV | No | No | Consider | Yes — 40mg/kg (max 2g) |
| Age | Preferred Device | Interface | DPI Suitable? |
|---|---|---|---|
| <2 yr | pMDI + spacer | Face mask | No |
| 2–4 yr | pMDI + spacer | Mouthpiece or mask | No |
| ≥5 yr | pMDI + spacer or DPI | Mouthpiece | Yes (if technique adequate) |
| Acute (any age) | Nebuliser | Mask or mouthpiece | No — DPI contraindicated |