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🌿 Nutrition Assessment Guide
MUST Scoring • Enteral Feeding • Refeeding Syndrome • GCC Nutritional Context

MUST — Malnutrition Universal Screening Tool

Purpose: The MUST is a validated, 5-step screening tool for identifying adults who are malnourished or at risk of malnutrition. Steps 1–3 generate a score; steps 4–5 guide management.
🔢 MUST Interactive Calculator
1 BMI Score
2 Unplanned Weight Loss (past 3–6 months)

Optional: calculate % weight loss

3 Acute Disease Effect
MUST TOTAL SCORE

Mini Nutritional Assessment (MNA) — Short Form

👴 MNA-SF (For Elderly Patients ≥ 65 years)
Screening Score: 12–14 = Normal nutrition status • 8–11 = At risk of malnutrition • 0–7 = Malnourished. Score < 11 indicates malnutrition risk — proceed to full MNA or refer dietitian.
QuestionScoring
A. Has food intake declined over the past 3 months due to loss of appetite, digestive problems, chewing or swallowing difficulties?0 = severe; 1 = moderate; 2 = no decrease
B. Weight loss during the last 3 months?0 = >3kg; 1 = unknown; 2 = 1–3kg; 3 = no loss
C. Mobility?0 = bed/chair-bound; 1 = able to get out but not outside; 2 = goes outside
D. Has the patient suffered psychological stress or acute disease in the past 3 months?0 = yes; 2 = no
E. Neuropsychological problems?0 = severe dementia or depression; 1 = mild; 2 = none
F1. BMI (kg/m²)0 = <19; 1 = 19–21; 2 = 21–23; 3 = ≥23
F2. Calf circumference (if BMI unavailable)0 = <31cm; 3 = ≥31cm

GLIM Criteria for Malnutrition Diagnosis

📋 Global Leadership Initiative on Malnutrition (GLIM 2018)

Requires at least 1 phenotypic AND 1 aetiologic criterion to diagnose malnutrition.

Phenotypic Criteria

  • Unintentional weight loss >5% in 6 months or >10% beyond 6 months
  • Low BMI: <20 kg/m² (age <70) or <22 kg/m² (age ≥70)
  • Reduced muscle mass (by validated body composition measure)

Aetiologic Criteria

  • Reduced food intake or assimilation (<50% of requirements for >1 week, or any reduction >2 weeks, or chronic GI impairment)
  • Disease burden / inflammation (acute injury/disease or chronic disease)

Nutritional History & Physical Examination

💬 History Questions
  • Appetite: any decrease over the past 1–3 months?
  • 24-hour diet recall: meals, snacks, fluids
  • Swallowing difficulty (dysphagia): refer SLT if present
  • GI symptoms: nausea, vomiting, diarrhoea, constipation, abdominal pain
  • Recent unintentional weight changes
  • Dietary restrictions: allergies, religious, ethical
  • Functional ability: able to shop, cook, self-feed?
  • Social factors: lives alone, food insecurity
🔎 Physical Examination Signs

Muscle Wasting

  • Temporal muscle: hollowing above zygomatic arch
  • Deltoid/shoulder: prominent acromion process
  • Thenar eminence flattening
  • Quadriceps wasting (squat test)

Subcutaneous Fat Loss

  • Orbital fat: sunken eyes
  • Triceps skinfold < 10th percentile

Oedema (masks weight loss)

  • Pitting oedema of ankles and sacrum
  • Ascites (hepatic disease)

Energy Requirements

Simple Weight-Based Estimates
Clinical SituationEnergy TargetNotes
Maintenance (stable, non-stressed)25–30 kcal/kg/dayUse actual body weight
Nutritional repletion (malnourished)30–35 kcal/kg/dayIncrease gradually to avoid refeeding
Obesity (BMI > 30)20–25 kcal/kg/dayUse adjusted body weight
ICU (critically ill)25–30 kcal/kg/dayAvoid overfeeding; indirect calorimetry ideal
ICU early phase (day 1–3)50–70% of targetTrophic/permissive underfeeding
ICU Note: Indirect calorimetry remains the gold standard for energy measurement in critical illness. Predictive equations have up to 40% error in ICU patients.
🔢 Harris-Benedict Equation Calculator

Protein Requirements

🥪 Protein by Clinical Condition
ConditionProtein Requirement
Healthy maintenance0.8 g/kg/day
General hospitalised patient1.2–1.5 g/kg/day
ICU / Critical illness1.5–2.0 g/kg/day
Burns / Major trauma2.0–2.5 g/kg/day
CKD (non-dialysis)0.6–0.8 g/kg/day
Haemodialysis / CRRT1.2–1.5 g/kg/day
Peritoneal dialysis1.2–1.5 g/kg/day
Hepatic failure (compensated)1.2–1.5 g/kg/day
Post-bariatric surgery60–80 g/day minimum

Carbohydrate & Fat

🏰 Carbohydrates
  • 50–60% of total daily energy intake
  • Glucose tolerance impaired in critical illness — monitor blood glucose closely
  • Maximum IV glucose infusion: 4–5 mg/kg/min
  • Target blood glucose in ICU: 6–10 mmol/L
  • Avoid hypoglycaemia (<4 mmol/L) — associated with poor outcome
🧔 Fats
  • 30–35% of total energy intake
  • Omega-3 fatty acids (EPA/DHA): anti-inflammatory benefit — consider in ARDS, sepsis
  • MCT/LCT lipid emulsions preferred in PN (Smoflipid, ClinOleic)
  • Serum triglycerides: <4.5 mmol/L before initiating lipid PN
  • Monitor triglycerides every 48–72h during PN

Micronutrients — GCC Focus

💊 Key Micronutrient Deficiencies in GCC
MicronutrientGCC PrevalenceClinical RelevanceAction
Vitamin D>90% deficientBone health, immunity, muscle function; sun avoidance due to heat/cultureSupplement: 1000–4000 IU/day; check 25-OH-D level
IronCommon in womenIron deficiency anaemia; fatigue, reduced immunityDietary: dates, red meat, lentils; supplement if Hb <12 g/dL women
Vitamin B12Vegans, elderlyMegaloblastic anaemia, peripheral neuropathy1000 mcg IM monthly or oral high-dose if deficient
ZincWound patientsWound healing, immune function, tasteZinc sulfate 220 mg oral BD; replace in burns/wounds
SeleniumICU patientsAntioxidant defence; low in critical illnessIV replacement in ICU: 500–1000 mcg/day (first 2–3 days)
Thiamine (B1)Refeeding riskEssential before refeeding malnourished patients200–300 mg IV before starting nutrition
🏭 GCC Diet Context
  • Traditional Arabic diet: rice, lamb/chicken, bread, dates, laban (yoghurt), ghee
  • High refined carbohydrate intake — white rice, white bread, sweets (halwa)
  • Obesity epidemic: UAE, Saudi Arabia, Kuwait among world's highest obesity rates
  • T2DM: 15–25% prevalence in GCC adults
  • Ramadan fasting: 29–30 days; impacts meal timing, hydration, medications
  • Hospitalised patients: may request exemption — discuss with patient and family sensitively
  • Tube-fed patients during Ramadan: discuss whether feeds should pause at dawn if culturally important
  • Sesame allergy: notably prevalent in Middle East — check formula ingredients

Nasogastric (NG) Tube Feeding

💉 Indications for NG Tube Feeding
🔍 NG Tube Position Verification
NEVER use the blue litmus paper (whoosh) test — it is not safe and is no longer accepted practice. This method has caused patient deaths.
MethodStandardNotes
pH testing of aspirateGold standard (routine)pH <5.5 confirms gastric placement. If pH ≥6 or no aspirate — do not feed; obtain CXR.
Chest X-ray (CXR)Required for first insertionAll new NG tube insertions require CXR confirmation before first use. Tube tip should be below diaphragm.
Whoosh / blue litmus paperNOT acceptableDo not use — not sensitive or specific for gastric placement.
CapnographyEmerging / specialistCan detect CO2 if tube in airway — adjunct only.
Starting & Advancing NG Feeds

Starting Rate

  • Start at 30–50 mL/hr
  • Increase by 20–30 mL/hr every 4–8 hours
  • Reach target rate within 24–48 hours
  • Target rate: typically 60–80 mL/hr for standard formula
  • In malnourished: start lower (10–20 mL/hr) to avoid refeeding syndrome

Gastric Residual Volume (GRV)

  • Check GRV every 4–6 hours
  • Accept GRV up to 300–500 mL in ICU
  • Do not routinely stop feeds for GRV <500 mL
  • If GRV >500 mL: hold feed 1 hour, reassess, consider prokinetics
  • Elevated GRV does not reliably predict aspiration

Prokinetic Agents for High GRV / Gastroparesis

DrugDoseNotes
Metoclopramide10 mg IV/oral TDS (max 5 days)First line; risk of extrapyramidal side effects with prolonged use
Erythromycin250 mg IV/oral TDS × 3–5 daysLow-dose motilin agonist; tachyphylaxis after 5–7 days
Domperidone10 mg oral TDSDoes not cross BBB; fewer neurological SE; QT prolongation risk

PEG & Post-Pyloric Feeding

🔧 PEG (Percutaneous Endoscopic Gastrostomy)

Indications

  • Long-term enteral nutrition (>4 weeks anticipated)
  • Motor neurone disease, stroke, head/neck cancer
  • Unable to maintain adequate oral intake chronically

Post-PEG Care

  • First feed: 4–6 hours post-insertion if uncomplicated
  • Site care: clean daily with saline/water; rotate external disc ±360° daily
  • Check balloon water: 5–10 mL every 4 weeks (balloon PEG)
  • Flush: 30 mL water before and after each feed and medication
  • Watch for: buried bumper syndrome, leakage, granulation tissue, infection
📈 NJ / Post-Pyloric Feeding

Indications

  • High aspiration risk (recurrent aspiration pneumonia)
  • Acute pancreatitis (nasojejunal preferred over NG)
  • Gastroparesis refractory to prokinetics
  • Gastric outlet obstruction

Key Points

  • Dobhoff (fine-bore NJ) tube: requires radiological or endoscopic confirmation
  • No pH check — position must be confirmed by X-ray
  • Continuous feeding preferred (no large boluses)
  • Semi-elemental or elemental formulas may be better tolerated

Standard Enteral Feed Formulas

🍼 Common Formula Types
FormulaEnergy DensityFeaturesUse
Jevity 1.01.0 kcal/mLFibre-containing, low residueStandard; bowel motility, constipation prevention
Osmolite 1.01.0 kcal/mLFibre-free, low osmolalityStandard; post-operative, CXR-confirmed NGT
Isosource HN1.0 kcal/mLHigh nitrogen (protein)Increased protein needs
Jevity 1.51.5 kcal/mLHigh energy + fibreFluid-restricted patients
TwoCal HN2.0 kcal/mLVery high energy & proteinSevere fluid restriction, ICU
Peptamen1.0 kcal/mLSemi-elemental (peptides)GI malabsorption, pancreatitis, short bowel
Glucerna1.0 kcal/mLLow glycaemic indexDiabetes mellitus, stress hyperglycaemia

Common Complications & Management

Enteral Feeding Complications
ComplicationCausesManagement
DiarrhoeaAntibiotic-associated, formula intolerance (osmolality, rate), C. difficile, medications (sorbitol-based)Check C. diff; switch to fibre-containing formula; reduce rate; review medications; probiotics (clinical guidance)
ConstipationLow fibre, dehydration, opioids, immobilityIncrease water flushes; switch to fibre formula; laxatives; mobilise
Nausea / VomitingHigh GRV, infection, medicationsReduce rate; check GRV; prokinetics; consider post-pyloric feeding
AspirationHOB flat, high GRV, impaired airway protectionHOB 30–45°; confirm tube position; reduce rate; consider PEG or NJ
Tube blockageInadequate flushing, crushed medicationsFlush 30 mL water every 4h and after meds; use pancreatic enzyme/Coke flush; replace tube if blocked
Refeeding syndromeMalnourished patient; see Tab 4Start low, go slow; thiamine; electrolyte monitoring
HOB reminder: Always maintain Head-of-Bed elevation at 30–45° during and for 30 minutes after enteral feeding to reduce aspiration risk.
💊 Drug Administration via NG Tube

Parenteral Nutrition (PN)

💰 When to Use PN
Enteral nutrition is always preferred when the GI tract is functional. Use PN only when enteral route is not available, not tolerated, or contraindicated for >3 days.

PN Indications

  • GI obstruction, paralytic ileus
  • Severe short bowel syndrome
  • High-output fistula (enteral not tolerated)
  • Severe malabsorption (mesenteric ischaemia)
  • Enteral nutrition contraindicated (>3 days)
  • Post-op: complex GI surgery, anastomotic leak

PN Contraindications / Caution

  • Functional GI tract available — use EN
  • Expected PN duration <5 days (risk > benefit)
  • Terminal illness where nutrition will not benefit quality of life
  • Untreated severe electrolyte abnormalities
💋 TPN vs Peripheral PN
FeatureTotal PN (TPN)Peripheral PN (PPN)
RouteCentral venous catheter (CVC), PICCPeripheral IV cannula
OsmolalityUp to 3000 mOsm/L<900 mOsm/L (risk of phlebitis)
DurationShort or long-termShort-term only (typically <10–14 days)
Energy provisionFull nutritional requirementsPartial — cannot provide full needs
Dedicated lumenRequired — no other drugs via PN lumenDedicated cannula required
📋 PN Components
ComponentPurposeNotes
Dextrose (glucose)Energy (3.4 kcal/g)Max infusion rate 4–5 mg/kg/min; hyperglycaemia common
Amino acidsProtein substrate (4 kcal/g)Standard 15% solution; glutamine may be added in ICU
Lipid emulsionEnergy + essential fatty acids (9 kcal/g)Smoflipid, ClinOleic preferred; check TGs <4.5 before starting
Water-soluble vitaminsB vitamins, vitamin CAdd daily; Cernevit or Soluvit
Fat-soluble vitaminsA, D, E, KAdd daily to lipid phase; Vitalipid
Trace elementsZinc, selenium, copper, iodine, manganeseAdd daily; Additrace or Tracutil
ElectrolytesNa, K, Ca, Mg, PhosphateAdded according to daily monitoring results
📊 PN Monitoring Schedule

Daily Monitoring

  • Blood glucose (every 4–6 hours initially)
  • Electrolytes: Na, K, bicarbonate
  • Phosphate (critical for refeeding)
  • Magnesium, Calcium
  • Fluid balance / weight
  • Line site inspection

2–3× Weekly

  • LFTs (ALT, AST, ALP, bilirubin)
  • Triglycerides (if lipid PN)
  • FBC, clotting
  • Urea & creatinine
  • Trace elements (weekly in long-term PN)
PN Complications
ComplicationPrevention / Management
HyperglycaemiaTarget 6–10 mmol/L; insulin infusion titration; reduce glucose rate; avoid overfeeding
HypertriglyceridaemiaStop lipid if TG >5 mmol/L; resume at lower rate when TG <4.5
PN-associated liver disease (PNALD)Use cyclic PN (off 8–12h); minimise duration; use Smoflipid (omega-3 containing); start EN as soon as possible
Line-related bloodstream infection (CRBSI)Strict aseptic technique; dedicated PN lumen; no blood draws from PN line; change tubing every 24h (with bag change)
OverfeedingAvoid exceeding 20–25 kcal/kg/day; hypercapnia (excess dextrose); hyperglycaemia; hepatic steatosis
Refeeding syndromeSee section below — applies equally to PN

⚠ Refeeding Syndrome

Refeeding syndrome is a potentially fatal electrolyte and metabolic disturbance occurring in malnourished patients when nutrition is reintroduced. The hallmark is hypophosphataemia caused by massive intracellular shifts of phosphate, potassium, and magnesium.
📋 Pathophysiology
🛑 NICE High-Risk Criteria for Refeeding Syndrome

Patient is at HIGH RISK if they have ONE or more of the following:

BMI < 16 kg/m²
Unintentional weight loss > 15% in the past 3–6 months
Little or no nutritional intake for more than 10 days
Low levels of potassium, phosphate, or magnesium before feeding starts

OR TWO or more of:

BMI < 18.5 kg/m²
Unintentional weight loss > 10% in 3–6 months
Little or no nutritional intake for >5 days
History: alcohol misuse, insulin use, antacids, diuretics, or chemotherapy

High-risk groups: anorexia nervosa, chronic alcoholism, cancer cachexia, post-operative starvation >5 days, homelessness/malnutrition

Refeeding Syndrome Management Protocol
1BEFORE starting nutrition
  • Give Thiamine (Vitamin B1) 200–300 mg IV immediately before first feed (prevents Wernicke's encephalopathy)
  • Check baseline electrolytes: phosphate, potassium, magnesium, sodium
  • Correct any electrolyte deficits before commencing nutrition
  • B-vitamin complex supplementation (Pabrinex or equivalent)
2Start feeds SLOWLY
  • Maximum 10 kcal/kg/day for the first 2 days (5 kcal/kg/day if extreme risk)
  • Increase by 33% every 2 days if electrolytes stable
  • Reach full target over 4–7 days
  • Do not restrict sodium — may worsen oedema by causing ADH release
3Daily electrolyte monitoring
  • Phosphate, potassium, magnesium — daily for first 2 weeks
  • Replace electrolytes proactively and aggressively:
    — Phosphate: IV Phosphate replacement if <0.6 mmol/L
    — Potassium: KCl oral/IV per local protocol
    — Magnesium: IV magnesium sulphate if severe depletion
  • Monitor fluid balance, cardiac rhythm
  • Blood glucose every 4–6 hours
Critical warning: If phosphate falls below 0.32 mmol/L — STOP feeds, inform medical team immediately, commence IV phosphate replacement urgently.

GCC-Specific Nutritional Issues

🌐 Obesity & Diabetes Epidemic
  • UAE, Saudi Arabia, Kuwait, Qatar among world's highest obesity prevalence
  • Adult obesity rates: 30–40% in many GCC populations
  • Type 2 diabetes: 15–25% prevalence (IDF data); highest globally
  • Medical nutrition therapy (MNT) is a cornerstone of diabetes management
  • Bariatric surgery increasing: post-op nutritional support critical (B12, iron, Ca, vit D)
  • Dietitian referral mandatory post-bariatric surgery
🌎 Ramadan Fasting in Hospital
  • Fasting from dawn (Fajr) to sunset (Maghrib) — typically 12–16 hours
  • Iftar (break fast at sunset): major meal; Suhoor (pre-dawn): lighter meal
  • Dehydration risk — especially summer in GCC; monitor fluid balance
  • DM patients: medication timing must be adjusted (consult physician/pharmacist)
  • Hospitalised patients: most Islamic scholars permit exemption when unwell — discuss sensitively
  • Tube-fed patients: if culturally important, discuss pausing feeds during daylight with patient & family
  • IV fluids: not considered breaking fast by most scholars — continue if clinically needed
Vitamin D Deficiency
  • >90% of GCC population deficient despite intense sunshine
  • Reasons: cultural dress, sun avoidance, limited outdoor activity, high melanin content
  • Deficiency defined as 25-OH-Vitamin D <50 nmol/L (20 ng/mL)
  • Insufficiency: 50–75 nmol/L
  • Repletion: loading dose 50,000 IU weekly × 8 weeks; maintenance 1,500–2,000 IU/day
  • Associated with: osteoporosis, falls, immune dysfunction, depression, T2DM
🩹 Iron Deficiency & Anaemia
  • Particularly common in women of reproductive age in GCC
  • Dietary sources: red meat, lamb liver, dates (natural iron in GCC diet), lentils, chickpeas
  • Vitamin C enhances non-haem iron absorption — advise with meals
  • Tea and coffee inhibit iron absorption — avoid 1 hour either side of meals
  • Oral ferrous sulfate 200 mg TDS; take on empty stomach if tolerated
  • IV iron (Ferinject) for intolerance, poor absorption, or severe anaemia
📌 Dietitian Referral Criteria
  • MUST score ≥ 2 (high risk)
  • Pre-operative complex or major surgery
  • Renal disease (CKD stage 3–5, dialysis)
  • Hepatic failure or cirrhosis
  • Inflammatory bowel disease
  • Eating disorders (anorexia nervosa, bulimia)
  • Post-bariatric surgery (mandatory)
  • Diabetes mellitus (MNT)
  • Oncology — cancer cachexia
  • Any patient requiring PN (review within 48h)
📌 Quick Reference: MUST Scoring Card
MUST TotalRisk CategoryAction
0Low riskRoutine clinical care; reassess weekly (hospital) / monthly (community)
1Medium riskObserve; document 3-day food intake; if inadequate, follow local policy; reassess weekly
≥ 2High riskTreat: refer dietitian; initiate nutrition support; set nutrition goals; monitor regularly

📝 Knowledge Quiz — Nutrition Assessment

1. A patient has a BMI of 17.8, unplanned weight loss of 12% over 3 months, and has been acutely ill with no oral intake for 6 days. What is their MUST score?
2. What is the GOLD STANDARD method for confirming NG tube position before FIRST use?
3. Which electrolyte abnormality is the HALLMARK of refeeding syndrome?
4. What protein requirement is recommended for a critically ill ICU patient?
5. What must be given BEFORE starting any nutrition in a patient at high risk of refeeding syndrome?
6. A patient in ICU has a gastric residual volume (GRV) of 350 mL. What is the correct action?
7. Which feature is UNIQUE to post-pyloric (NJ) tube feeding?
8. What is the most prevalent micronutrient deficiency in the GCC population?
9. Which drug should NOT be crushed for administration via NG tube?
10. According to NICE criteria, which patient is at HIGH risk of refeeding syndrome?