Purpose: The MUST is a validated, 5-step screening tool for identifying adults who are malnourished or at risk of malnutrition. Steps 1–3 generate a score; steps 4–5 guide management.
🔢 MUST Interactive Calculator
1BMI Score
2Unplanned Weight Loss (past 3–6 months)
Optional: calculate % weight loss
3Acute Disease Effect
MUST TOTAL SCORE
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Mini Nutritional Assessment (MNA) — Short Form
👴 MNA-SF (For Elderly Patients ≥ 65 years)
Screening Score: 12–14 = Normal nutrition status • 8–11 = At risk of malnutrition • 0–7 = Malnourished. Score < 11 indicates malnutrition risk — proceed to full MNA or refer dietitian.
Question
Scoring
A. Has food intake declined over the past 3 months due to loss of appetite, digestive problems, chewing or swallowing difficulties?
0 = severe; 1 = moderate; 2 = no decrease
B. Weight loss during the last 3 months?
0 = >3kg; 1 = unknown; 2 = 1–3kg; 3 = no loss
C. Mobility?
0 = bed/chair-bound; 1 = able to get out but not outside; 2 = goes outside
D. Has the patient suffered psychological stress or acute disease in the past 3 months?
0 = yes; 2 = no
E. Neuropsychological problems?
0 = severe dementia or depression; 1 = mild; 2 = none
F1. BMI (kg/m²)
0 = <19; 1 = 19–21; 2 = 21–23; 3 = ≥23
F2. Calf circumference (if BMI unavailable)
0 = <31cm; 3 = ≥31cm
GLIM Criteria for Malnutrition Diagnosis
📋 Global Leadership Initiative on Malnutrition (GLIM 2018)
Requires at least 1 phenotypic AND 1 aetiologic criterion to diagnose malnutrition.
Phenotypic Criteria
Unintentional weight loss >5% in 6 months or >10% beyond 6 months
Functional ability: able to shop, cook, self-feed?
Social factors: lives alone, food insecurity
🔎 Physical Examination Signs
Muscle Wasting
Temporal muscle: hollowing above zygomatic arch
Deltoid/shoulder: prominent acromion process
Thenar eminence flattening
Quadriceps wasting (squat test)
Subcutaneous Fat Loss
Orbital fat: sunken eyes
Triceps skinfold < 10th percentile
Oedema (masks weight loss)
Pitting oedema of ankles and sacrum
Ascites (hepatic disease)
Energy Requirements
⚡ Simple Weight-Based Estimates
Clinical Situation
Energy Target
Notes
Maintenance (stable, non-stressed)
25–30 kcal/kg/day
Use actual body weight
Nutritional repletion (malnourished)
30–35 kcal/kg/day
Increase gradually to avoid refeeding
Obesity (BMI > 30)
20–25 kcal/kg/day
Use adjusted body weight
ICU (critically ill)
25–30 kcal/kg/day
Avoid overfeeding; indirect calorimetry ideal
ICU early phase (day 1–3)
50–70% of target
Trophic/permissive underfeeding
ICU Note: Indirect calorimetry remains the gold standard for energy measurement in critical illness. Predictive equations have up to 40% error in ICU patients.
Flush 30 mL water every 4h and after meds; use pancreatic enzyme/Coke flush; replace tube if blocked
Refeeding syndrome
Malnourished patient; see Tab 4
Start low, go slow; thiamine; electrolyte monitoring
HOB reminder: Always maintain Head-of-Bed elevation at 30–45° during and for 30 minutes after enteral feeding to reduce aspiration risk.
💊 Drug Administration via NG Tube
Flush with 30 mL water before and after each medication
Never crush: modified-release tablets (SR/MR/XL), enteric-coated tablets, gelatin capsules
Acceptable to crush: immediate-release tablets (confirm with pharmacist)
Omeprazole: use dispersible tablet or oral suspension — do not crush standard capsule
Phenytoin: significant NG feed interaction — hold feeds 1–2 hours before and after
Warfarin, levothyroxine: absorption affected by feeds — time carefully
Always consult pharmacist for any NG medication queries
Parenteral Nutrition (PN)
💰 When to Use PN
Enteral nutrition is always preferred when the GI tract is functional. Use PN only when enteral route is not available, not tolerated, or contraindicated for >3 days.
PN Indications
GI obstruction, paralytic ileus
Severe short bowel syndrome
High-output fistula (enteral not tolerated)
Severe malabsorption (mesenteric ischaemia)
Enteral nutrition contraindicated (>3 days)
Post-op: complex GI surgery, anastomotic leak
PN Contraindications / Caution
Functional GI tract available — use EN
Expected PN duration <5 days (risk > benefit)
Terminal illness where nutrition will not benefit quality of life
Untreated severe electrolyte abnormalities
💋 TPN vs Peripheral PN
Feature
Total PN (TPN)
Peripheral PN (PPN)
Route
Central venous catheter (CVC), PICC
Peripheral IV cannula
Osmolality
Up to 3000 mOsm/L
<900 mOsm/L (risk of phlebitis)
Duration
Short or long-term
Short-term only (typically <10–14 days)
Energy provision
Full nutritional requirements
Partial — cannot provide full needs
Dedicated lumen
Required — no other drugs via PN lumen
Dedicated cannula required
📋 PN Components
Component
Purpose
Notes
Dextrose (glucose)
Energy (3.4 kcal/g)
Max infusion rate 4–5 mg/kg/min; hyperglycaemia common
Amino acids
Protein substrate (4 kcal/g)
Standard 15% solution; glutamine may be added in ICU
Lipid emulsion
Energy + essential fatty acids (9 kcal/g)
Smoflipid, ClinOleic preferred; check TGs <4.5 before starting
Refeeding syndrome is a potentially fatal electrolyte and metabolic disturbance occurring in malnourished patients when nutrition is reintroduced. The hallmark is hypophosphataemia caused by massive intracellular shifts of phosphate, potassium, and magnesium.
📋 Pathophysiology
During starvation: body depletes intracellular phosphate, potassium, magnesium — serum levels may appear normal
Correct any electrolyte deficits before commencing nutrition
B-vitamin complex supplementation (Pabrinex or equivalent)
2Start feeds SLOWLY
Maximum 10 kcal/kg/day for the first 2 days (5 kcal/kg/day if extreme risk)
Increase by 33% every 2 days if electrolytes stable
Reach full target over 4–7 days
Do not restrict sodium — may worsen oedema by causing ADH release
3Daily electrolyte monitoring
Phosphate, potassium, magnesium — daily for first 2 weeks
Replace electrolytes proactively and aggressively:
— Phosphate: IV Phosphate replacement if <0.6 mmol/L
— Potassium: KCl oral/IV per local protocol
— Magnesium: IV magnesium sulphate if severe depletion
Monitor fluid balance, cardiac rhythm
Blood glucose every 4–6 hours
Critical warning: If phosphate falls below 0.32 mmol/L — STOP feeds, inform medical team immediately, commence IV phosphate replacement urgently.
GCC-Specific Nutritional Issues
🌐 Obesity & Diabetes Epidemic
UAE, Saudi Arabia, Kuwait, Qatar among world's highest obesity prevalence
Adult obesity rates: 30–40% in many GCC populations
Type 2 diabetes: 15–25% prevalence (IDF data); highest globally
Medical nutrition therapy (MNT) is a cornerstone of diabetes management
Bariatric surgery increasing: post-op nutritional support critical (B12, iron, Ca, vit D)
Dietitian referral mandatory post-bariatric surgery
🌎 Ramadan Fasting in Hospital
Fasting from dawn (Fajr) to sunset (Maghrib) — typically 12–16 hours
Iftar (break fast at sunset): major meal; Suhoor (pre-dawn): lighter meal
Dehydration risk — especially summer in GCC; monitor fluid balance
DM patients: medication timing must be adjusted (consult physician/pharmacist)
Hospitalised patients: most Islamic scholars permit exemption when unwell — discuss sensitively
Tube-fed patients: if culturally important, discuss pausing feeds during daylight with patient & family
IV fluids: not considered breaking fast by most scholars — continue if clinically needed
☀ Vitamin D Deficiency
>90% of GCC population deficient despite intense sunshine
Reasons: cultural dress, sun avoidance, limited outdoor activity, high melanin content
Deficiency defined as 25-OH-Vitamin D <50 nmol/L (20 ng/mL)
1. A patient has a BMI of 17.8, unplanned weight loss of 12% over 3 months, and has been acutely ill with no oral intake for 6 days. What is their MUST score?
2. What is the GOLD STANDARD method for confirming NG tube position before FIRST use?
3. Which electrolyte abnormality is the HALLMARK of refeeding syndrome?
4. What protein requirement is recommended for a critically ill ICU patient?
5. What must be given BEFORE starting any nutrition in a patient at high risk of refeeding syndrome?
6. A patient in ICU has a gastric residual volume (GRV) of 350 mL. What is the correct action?
7. Which feature is UNIQUE to post-pyloric (NJ) tube feeding?
8. What is the most prevalent micronutrient deficiency in the GCC population?
9. Which drug should NOT be crushed for administration via NG tube?
10. According to NICE criteria, which patient is at HIGH risk of refeeding syndrome?